Mussel-inspired cryogels for promoting wound regeneration through photobiostimulation, modulating inflammatory responses and suppressing bacterial invasion.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr03095f
Abstract: Wound healing is a complex and dynamic process, and involves a series of events, which create a unique microenvironment at the wound sites. It is highly desirable to develop multi-functional skin substitutes which can play… read more here.
Keywords: wound healing; inflammatory responses; mussel inspired; wound ... See more keywords
Gut Microenvironment and Bacterial Invasion in Paediatric Inflammatory Bowel Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pediatric Gastroenterology and Nutrition"
DOI: 10.1097/mpg.0000000000002848
Abstract: Supplemental Digital Content is available in the text ABSTRACT Objectives: Host-microbial relationship is disrupted in inflammatory bowel diseases (IBD). We hypothesized that altered gut luminal microenvironment can impact microbial virulence in IBD, leading to disruption… read more here.
Keywords: intestinal aspirates; inflammatory bowel; ibd; invasion ... See more keywords
Keeping it clean: clot biofilm to wall out bacterial invasion
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14309
Abstract: There are already many links between hemostasis and innate immunity, which have a strong connection in terms of a common evolutionary ancestry as immediate responses to injury. In addition to the commonalities between coagulation and… read more here.
Keywords: fibrin biofilms; fibrin; keeping clean; fibrin sheets ... See more keywords
Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion
Sign Up to like & getrecommendations! Published in 2017 at "mBio"
DOI: 10.1128/mbio.02128-16
Abstract: ABSTRACT To understand the role of glycosaminoglycans in bacterial cellular invasion, xylosyltransferase-deficient mutants of Chinese hamster ovary (CHO) cells were created using clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene… read more here.
Keywords: invasion; group streptococcus; host; cellular invasion ... See more keywords
The Transmembrane Mucin MUC1 Facilitates β1-Integrin-Mediated Bacterial Invasion
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DOI: 10.1128/mbio.03491-20
Abstract: Bacteria can exploit membrane receptor integrins for cellular invasion, either by direct binding of bacterial adhesins or utilizing extracellular matrix components. MUC1 is a large transmembrane glycoprotein expressed by most epithelial cells that can have… read more here.
Keywords: muc1; integrin mediated; invasion; receptor ... See more keywords
Microbial and Host Factors That Affect Bacterial Invasion of the Gingiva
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Dental Research"
DOI: 10.1177/0022034520922134
Abstract: Periodontitis is a chronic inflammation of the periodontium caused by the loss of homeostasis between subgingival biofilms and susceptible hosts. Bacterial invasion into the gingival tissue and persistent infection are major events that lead to… read more here.
Keywords: host factors; invasion; invasion gingiva; microbial host ... See more keywords
Group B Streptococcus-Induced Macropinocytosis Contributes to Bacterial Invasion of Brain Endothelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11040474
Abstract: Bacterial meningitis is defined as serious inflammation of the central nervous system (CNS) in which bacteria infect the blood–brain barrier (BBB), a network of highly specialized brain endothelial cells (BECs). Dysfunction of the BBB is… read more here.
Keywords: endothelial cells; macropinocytosis; bacterial invasion; invasion ... See more keywords