Risk factors and microbiological characteristics: from bacterial keratitis with hypopyon to keratitis-related endophthalmitis
Sign Up to like & getrecommendations! Published in 2022 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-022-05657-y
Abstract: To compare the clinical and microbiological characteristics in patients with bacterial keratitis with hypopyon (BKH), bacterial keratitis-related endophthalmitis (BKE), and bacterial endophthalmitis without keratitis (BE). Data from all inpatients who were clinically diagnosed with BKH,… read more here.
Keywords: endophthalmitis; keratitis; bacterial keratitis; risk factors ... See more keywords
Alterations in the conjunctival surface bacterial microbiome in bacterial keratitis patients.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108418
Abstract: Microbial keratitis is an infectious disease of the eye, in which the cornea is inflamed. Under severe conditions, keratitis can lead to significant loss of vision and enucleation of the eye. Ocular trauma is the… read more here.
Keywords: bacterial keratitis; bacterial microbiome; keratitis patients; eye ... See more keywords
A Targeted Photosensitizer Mediated by Visible Light for Efficient Therapy of Bacterial Keratitis.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00461
Abstract: Bacterial keratitis is a serious bacterial infection of the cornea that can cause sight loss in severe cases because of the sharp decline of efficacious antibiotics. Herein, a targeted photosensitizer based on BODIPY severing as… read more here.
Keywords: bacterial keratitis; targeted photosensitizer; photosensitizer mediated; therapy ... See more keywords
Corneal lymphangiogenesis ameliorates corneal inflammation and edema in late stage of bacterial keratitis
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DOI: 10.1038/s41598-019-39876-x
Abstract: Lymphatic vessels play a crucial role in systemic immune response and regulation of tissue fluid homeostasis. Corneal lymphangiogenesis in bacterial keratitis has not been studied. In this study, we investigated the mechanism and the role… read more here.
Keywords: bacterial keratitis; late stage; keratitis; corneal lymphangiogenesis ... See more keywords
Medication Burden for Patients With Bacterial Keratitis.
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DOI: 10.1097/ico.0000000000001942
Abstract: PURPOSE To understand medication use and patient burden for treatment of bacterial keratitis (BK). METHODS A retrospective study was conducted examining medical records of adult patients with BK in an academic cornea practice. Data collected… read more here.
Keywords: medication burden; medication; bacterial keratitis; burden treatment ... See more keywords
Bacterial Keratitis: Clinical Features, Causative Organisms, and Outcome During a 13-year Study Period
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DOI: 10.1097/ico.0000000000003179
Abstract: Purpose: This study aimed to review clinical features, causative organisms, complications, and outcome of bacterial keratitis cases at a tertiary eye hospital. Methods: A retrospective study was conducted on clinically diagnosed bacterial keratitis cases from… read more here.
Keywords: bacterial keratitis; keratitis; features causative; causative organisms ... See more keywords
Empirical treatment of bacterial keratitis: an international survey of corneal specialists
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open Ophthalmology"
DOI: 10.1136/bmjophth-2016-000047
Abstract: Background/aims New antibiotic agents and changing susceptibility patterns may have changed the empirical treatment of bacterial keratitis. Our objective in this study was to survey cornea specialists’ practice patterns in the initial treatment of bacterial… read more here.
Keywords: treatment bacterial; bacterial keratitis; treatment; survey ... See more keywords
What empiric treatment should be given for suspected bacterial keratitis in Northern Italy?
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Ophthalmology"
DOI: 10.1177/11206721221112519
Abstract: There is a lack of epidemiological studies reporting bacteria profiles, susceptibility, and suggested empiric (first line) treatment in Northern Italy. Our internal audit of corneal scraping for microbial keratitis at University of Brescia reports 116… read more here.
Keywords: empiric treatment; bacterial keratitis; northern italy; keratitis ... See more keywords
Treatment of Severe Acute Bacterial Keratitis in Rabbits Using Continuous Topical Ocular Instillation with Norvancomycin
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DOI: 10.2147/dddt.s295874
Abstract: Purpose Efficacy of norvancomycin (NVCM) through continuous topical ocular instillation drug delivery (CTOIDD) system for treating severe acute bacterial keratitis infection with Staphylococcus aureus was investigated. Methods Rabbits with bacterial keratitis were treated using CTOIDD… read more here.
Keywords: keratitis; bacterial keratitis; acute bacterial; group ... See more keywords
Profiling of Diagnostic Information of and Latent Susceptibility to Bacterial Keratitis From the Perspective of Ocular Bacterial Microbiota
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.645907
Abstract: The ocular surface possesses its own bacterial microbiota. Once given a chance, opportunistic pathogens within ocular microbiota may lead to corneal infection like bacterial keratitis (BK). To reveal the possible factor that makes people vulnerable… read more here.
Keywords: microbiota; ocular microbiota; bacterial keratitis; bacterial microbiota ... See more keywords
Cyclodextrins Allow the Combination of Incompatible Vancomycin and Ceftazidime into an Ophthalmic Formulation for the Treatment of Bacterial Keratitis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910538
Abstract: Ceftazidime (CZ) and vancomycin (VA) are two antibiotics used to treat bacterial keratitis. Due to their physical incompatibility (formation of a precipitate), it is not currently possible to associate both molecules in a single container… read more here.
Keywords: vancomycin; bacterial keratitis; formulation; incompatibility ... See more keywords