ZnFe Layered Double Hydroxide Nanosheets Loaded with Cu Single‐Atom Nanozymes with Multi‐Enzyme‐Like Catalytic Activities as an Effective Treatment for Bacterial Keratitis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202411999
Abstract: Bacterial keratitis (BK) is a type of corneal inflammation resulting from bacterial infection in the eye. Although nanozymes have been explored as promising materials in corneal wound healing, currently available nanozymes lack sufficient catalytic activity… read more here.
Keywords: treatment; znfe; bacterial keratitis; znfe layered ... See more keywords
Risk factors and microbiological characteristics: from bacterial keratitis with hypopyon to keratitis-related endophthalmitis
Sign Up to like & getrecommendations! Published in 2022 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-022-05657-y
Abstract: To compare the clinical and microbiological characteristics in patients with bacterial keratitis with hypopyon (BKH), bacterial keratitis-related endophthalmitis (BKE), and bacterial endophthalmitis without keratitis (BE). Data from all inpatients who were clinically diagnosed with BKH,… read more here.
Keywords: endophthalmitis; keratitis; bacterial keratitis; risk factors ... See more keywords
Alterations in the conjunctival surface bacterial microbiome in bacterial keratitis patients.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108418
Abstract: Microbial keratitis is an infectious disease of the eye, in which the cornea is inflamed. Under severe conditions, keratitis can lead to significant loss of vision and enucleation of the eye. Ocular trauma is the… read more here.
Keywords: bacterial keratitis; bacterial microbiome; keratitis patients; eye ... See more keywords
Harnessing the Potential of a Nitroreductase-Responsive Fluorescent Probe for the Diagnosis of Bacterial Keratitis.
Sign Up to like & getrecommendations! Published in 2024 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.4c00234
Abstract: Bacterial keratitis, an ocular emergency, is the predominant cause of infectious keratitis. However, diagnostic procedures for it are invasive, time-consuming, and expeditious, thereby limiting effective treatment for the disease in the clinic. It is imperative… read more here.
Keywords: diagnosis bacterial; bacterial keratitis; keratitis; probe ... See more keywords
Unlocking the Potential of Antimicrobial Peptides: Cutting-Edge Advances and Therapeutic Potential in Combating Bacterial Keratitis.
Sign Up to like & getrecommendations! Published in 2025 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.4c00594
Abstract: Bacterial keratitis is a prevalent, and severe corneal illness resulting from bacterial pathogens. Failure to administer a timely and suitable therapy may lead to corneal opacity, ulceration, significant vision impairment, or potential blindness. Current clinical… read more here.
Keywords: peptides cutting; bacterial keratitis; potential antimicrobial; keratitis ... See more keywords
A Targeted Photosensitizer Mediated by Visible Light for Efficient Therapy of Bacterial Keratitis.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00461
Abstract: Bacterial keratitis is a serious bacterial infection of the cornea that can cause sight loss in severe cases because of the sharp decline of efficacious antibiotics. Herein, a targeted photosensitizer based on BODIPY severing as… read more here.
Keywords: bacterial keratitis; targeted photosensitizer; photosensitizer mediated; therapy ... See more keywords
Engineering of a Mantis-Forelimb-Inspired Bioabsorbable Lens-like Ocular Therapeutic (BLOT) Device for Effective Bacterial Keratitis Treatment.
Sign Up to like & getrecommendations! Published in 2025 at "Nano letters"
DOI: 10.1021/acs.nanolett.5c03995
Abstract: Bacterial keratitis poses a significant global challenge due to rapid progression, antibiotic resistance, and corneal drug delivery difficulties. Facing the problems, we designed a mantis-forelimb-inspired bioabsorbable lens-like ocular therapeutic (BLOT) device with an oriented microneedle… read more here.
Keywords: keratitis; blot device; bacterial keratitis; treatment ... See more keywords
Corneal lymphangiogenesis ameliorates corneal inflammation and edema in late stage of bacterial keratitis
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39876-x
Abstract: Lymphatic vessels play a crucial role in systemic immune response and regulation of tissue fluid homeostasis. Corneal lymphangiogenesis in bacterial keratitis has not been studied. In this study, we investigated the mechanism and the role… read more here.
Keywords: bacterial keratitis; late stage; keratitis; corneal lymphangiogenesis ... See more keywords
Medication Burden for Patients With Bacterial Keratitis.
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DOI: 10.1097/ico.0000000000001942
Abstract: PURPOSE To understand medication use and patient burden for treatment of bacterial keratitis (BK). METHODS A retrospective study was conducted examining medical records of adult patients with BK in an academic cornea practice. Data collected… read more here.
Keywords: medication burden; medication; bacterial keratitis; burden treatment ... See more keywords
Bacterial Keratitis: Clinical Features, Causative Organisms, and Outcome During a 13-year Study Period
Sign Up to like & getrecommendations! Published in 2022 at "Cornea"
DOI: 10.1097/ico.0000000000003179
Abstract: Purpose: This study aimed to review clinical features, causative organisms, complications, and outcome of bacterial keratitis cases at a tertiary eye hospital. Methods: A retrospective study was conducted on clinically diagnosed bacterial keratitis cases from… read more here.
Keywords: bacterial keratitis; keratitis; features causative; causative organisms ... See more keywords
Empirical treatment of bacterial keratitis: an international survey of corneal specialists
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open Ophthalmology"
DOI: 10.1136/bmjophth-2016-000047
Abstract: Background/aims New antibiotic agents and changing susceptibility patterns may have changed the empirical treatment of bacterial keratitis. Our objective in this study was to survey cornea specialists’ practice patterns in the initial treatment of bacterial… read more here.
Keywords: treatment bacterial; bacterial keratitis; treatment; survey ... See more keywords