Targeting multiple genetic defects of mitochondrial diseases with a single bacterial lipoate protein ligase
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DOI: 10.1126/sciadv.aea8481
Abstract: Metabolic disorders caused by defects in energy metabolism can lead to many life-threatening diseases; their therapy remains elusive in most cases. Conventional gene therapy relies on the “one gene for one genetic defect” strategy. Here,… read more here.
Keywords: lipoate protein; genetic defects; multiple genetic; bacterial lipoate ... See more keywords