Improvement of extracellular bacterial protein production in Pichia pastoris by co-expression of endoplasmic reticulum residing GroEL-GroES.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2017.09.007
Abstract: Pichia pastoris is an established host system for heterologous protein expression. However, the potential productivity of this system can be limited. In this study, the Escherichia coli chaperones (GroES-GroEL) were expressed from the PGAP promoter… read more here.
Keywords: protein; production; bacterial protein; expression ... See more keywords
Semiprocessive Hyperglycosylation of Adhesin by Bacterial Protein N-Glycosyltransferases.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical biology"
DOI: 10.1021/acschembio.0c00848
Abstract: Processivity is an important feature of enzyme families such as DNA polymerases, polysaccharide synthases, and protein kinases, to ensure high fidelity in biopolymer synthesis and modification. Here, we reveal processive character in the family of… read more here.
Keywords: protein; protein glycosyltransferases; semiprocessive hyperglycosylation; bacterial protein ... See more keywords
Bacterial protein secretion systems: Game of types.
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001193
Abstract: Protein trafficking across the bacterial envelope is a process that contributes to the organisation and integrity of the cell. It is the foundation for establishing contact and exchange between the environment and the cytosol. It… read more here.
Keywords: systems game; bacterial protein; secretion systems; protein secretion ... See more keywords
Dynamics of Mycobacterium tuberculosis Ag85B Revealed by a Sensitive Enzyme-Linked Immunosorbent Assay
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DOI: 10.1128/mbio.00611-19
Abstract: Bacterial protein secretion contributes to host-pathogen interactions, yet the process and consequences of bacterial protein secretion during infection are poorly understood. We developed a sensitive ELISA to quantitate a protein (termed Ag85B) secreted by M.… read more here.
Keywords: bacterial protein; ag85b; secretion; protein secretion ... See more keywords
Bacterial Protein Tyrosine Phosphatases as Possible Targets for Antimicrobial Therapies in Response to Antibiotic Resistance
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DOI: 10.3390/antiox11122397
Abstract: The review is focused on the bacterial protein tyrosine phosphatases (PTPs) utilized by bacteria as virulence factors necessary for pathogenicity. The inhibition of bacterial PTPs could contribute to the arrest of the bacterial infection process.… read more here.
Keywords: protein tyrosine; phosphatases possible; tyrosine; bacterial protein ... See more keywords
The Bacterial Protein CNF1 as a Potential Therapeutic Strategy against Mitochondrial Diseases: A Pilot Study
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19071825
Abstract: The Escherichia coli protein toxin cytotoxic necrotizing factor 1 (CNF1), which acts on the Rho GTPases that are key regulators of the actin cytoskeleton, is emerging as a potential therapeutic tool against certain neurological diseases… read more here.
Keywords: bacterial protein; mitochondrial diseases; strategy mitochondrial; cnf1 ... See more keywords