Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-21144-0
Abstract: Base-pairing interactions mediate many intermolecular target recognition events. Even a single base-pair mismatch can cause a substantial difference in activity but how such changes influence the target search kinetics in vivo is unknown. Here, we… read more here.
Keywords: small rna; target; target search; base ... See more keywords
Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.01.11.475788
Abstract: Proteins from the bacterial small multidrug resistance (SMR) family are proton-coupled exporters of diverse antiseptics and antimicrobials, including polyaromatic cations and quaternary ammonium compounds. The transport mechanism of the Escherichia coli transporter, EmrE, has been… read more here.
Keywords: bacterial small; multidrug resistance; small multidrug; complex structurally ... See more keywords