Inhibiting Iron Mobilization from Bacterioferritin in Pseudomonas aeruginosa Impairs Biofilm Formation Irrespective of Environmental Iron Availability
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DOI: 10.1021/acsinfecdis.9b00398
Abstract: Although iron is essential for bacteria, the nutrient presents problems of toxicity and solubility. Bacteria circumvent these problems with the aid of iron storage proteins where Fe3+ is deposited and, when necessary, mobilized as Fe2+… read more here.
Keywords: bfd; pseudomonas aeruginosa; bfrb bfd; mobilization ... See more keywords
Protein encapsulation within the internal cavity of a bacterioferritin
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DOI: 10.1039/d2nr01780f
Abstract: The thermal and chemical stability of 24mer ferritins has led to attempts to exploit their naturally occurring nanoscale (8 nm) internal cavities for biotechnological applications. An area of increasing interest is the encapsulation of molecules… read more here.
Keywords: protein encapsulation; bacterioferritin; encapsulation; internal cavity ... See more keywords
Multiple Lineages of Nematode-Wolbachia Symbiosis in Supergroup F and Convergent Loss of Bacterioferritin in Filarial Wolbachia
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DOI: 10.1093/gbe/evad073
Abstract: The intracellular endosymbiotic proteobacteria Wolbachia have evolved across the phyla nematoda and arthropoda. In Wolbachia phylogeny, supergroup F is the only clade known so far with members from both arthropod and filarial nematode hosts and… read more here.
Keywords: bacterioferritin; loss; supergroup; wolbachia ... See more keywords
Mobilization of Iron Stored in Bacterioferritin Is Required for Metabolic Homeostasis in Pseudomonas aeruginosa
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DOI: 10.3390/pathogens9120980
Abstract: Iron homeostasis offers a significant bacterial vulnerability because pathogens obtain essential iron from their mammalian hosts, but host-defenses maintain vanishingly low levels of free iron. Although pathogens have evolved mechanisms to procure host-iron, these depend… read more here.
Keywords: homeostasis; metabolic homeostasis; mobilization iron; iron ... See more keywords