Optogenetic Modulation and Reprogramming of Bacteriorhodopsin‐Transfected Human Fibroblasts on Self‐Assembled Fullerene C60 Nanosheets
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Biosystems"
DOI: 10.1002/adbi.201800254
Abstract: Fullerenes have unique biocompatibility and photoelectric properties and are candidate materials for biomedical applications. Several cell membrane proteins in nature such as bacteriorhodopsin also have photoelectric properties. Highly expressible bacteriorhodopsin (HEBR) is a novel light‐sensitive… read more here.
Keywords: optogenetic modulation; human fibroblasts; self assembled; photoelectric properties ... See more keywords
A scenario for the origin of life: Volume regulation by bacteriorhodopsin required extremely voltage sensitive Na‐channels and very selective K‐channels
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202100210
Abstract: The osmotic activity produced by internal, non‐permeable, anionic nucleic acids and metabolites causes a persistent and life‐threatening cell swelling, or cellular edema, produced by the Gibbs‐Donnan effect. This evolutionary‐critical osmotic challenge must have been resolved… read more here.
Keywords: voltage sensitive; sensitive channels; bacteriorhodopsin; volume ... See more keywords
Investigation of factors influencing oxygen content in Halobacterium salinarum growth medium for improved bacteriorhodopsin production
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Industrial Chemistry"
DOI: 10.1007/s40090-019-0189-0
Abstract: Improving production of bacteriorhodopsin in the culture medium of Halobacterium salinarum confronts indeterminacy related to culture conditions. Several studies have revealed that high oxygen content increases the growth of Halobacterium salinarum whereas it down-regulates the… read more here.
Keywords: oxygen; production; bacteriorhodopsin production; halobacterium salinarum ... See more keywords
Quantifying the Native Energetics Stabilizing Bacteriorhodopsin by Single-Molecule Force Spectroscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Physical review letters"
DOI: 10.1103/physrevlett.125.068102
Abstract: We quantified the equilibrium (un)folding free energy ΔG_{0} of an eight-amino-acid region starting from the fully folded state of the model membrane-protein bacteriorhodopsin using single-molecule force spectroscopy. Analysis of equilibrium and nonequilibrium data yielded consistent,… read more here.
Keywords: single molecule; force spectroscopy; molecule force; spectroscopy ... See more keywords