A mucin-responsive hybrid two-component system controls Bacteroides thetaiotaomicron colonization and gut homeostasis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Microbiology"
DOI: 10.1007/s12275-022-1649-3
Abstract: The mammalian intestinal tract contains trillions of bacteria. However, the genetic factors that allow gut symbiotic bacteria to occupy intestinal niches remain poorly understood. Here, we identified genetic determinants required for Bacteroides thetaiotaomicron colonization in… read more here.
Keywords: bacteroides thetaiotaomicron; colonization; thetaiotaomicron colonization; colonization gut ... See more keywords
Characterization of a α-l-rhamnosidase from Bacteroides thetaiotaomicron with high catalytic efficiency of epimedin C.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.08.004
Abstract: In this study, a α-l-rhamnosidase gene from Bacteroides thetaiotaomicron VPI-5482 was cloned and expressed in Escherichia coli. The specific activity of rhamnosidase was 0.57 U/mg in LB medium with 0.1 mM Isopropyl β-d-Thiogalactoside (IPTG) induction at… read more here.
Keywords: bacteroides thetaiotaomicron; rhamnoside rhamnoside; epimedin; rhamnosidase ... See more keywords
Molecular insights into catalytic specificity of α-L-rhamnosidase from Bacteroides thetaiotaomicron by molecular docking and dynamics
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2020.137695
Abstract: Abstract Recently, a kind of α-L-rhamnosidase from Bacteroides thetaiotaomicron (BtRha) was characterized and studied for the hydrolysis of natural substrates. In order to investigate catalytic specificity of BtRha, three natural substrates, epimedin C, naringin, and… read more here.
Keywords: bacteroides thetaiotaomicron; docking dynamics; catalytic specificity; rhamnosidase ... See more keywords
Interactions between Kluyveromyces marxianus from cheese origin and the intestinal symbiont Bacteroides thetaiotaomicron: Impressive antioxidative effects
Sign Up to like & getrecommendations! Published in 2017 at "Lwt - Food Science and Technology"
DOI: 10.1016/j.lwt.2017.03.056
Abstract: The effects of yeast Kluyveromyces marxianus S-2-05, of cheese origin, were assessed on the intestine anaerobe symbiont Bacteroides thetaiotaomicron ATCC 29741 to unveil any changes in its antioxidant properties. To this end, these microorganisms were… read more here.
Keywords: symbiont bacteroides; bacteroides thetaiotaomicron; antioxidative effects; kluyveromyces marxianus ... See more keywords
Metabolism of multiple glycosaminoglycans by Bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-14509-4
Abstract: The human gut microbiota (HGM), which is critical to human health, utilises complex glycans as its major carbon source. Glycosaminoglycans represent an important, high priority, nutrient source for the HGM. Pathways for the metabolism of… read more here.
Keywords: glycosaminoglycans bacteroides; bacteroides thetaiotaomicron; metabolism; multiple glycosaminoglycans ... See more keywords
Engineering a surface endogalactanase into Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation
Sign Up to like & getrecommendations! Published in 2018 at "Nature microbiology"
DOI: 10.1038/s41564-018-0258-8
Abstract: Glycans are major nutrients for the human gut microbiota (HGM). Arabinogalactan proteins (AGPs) comprise a heterogenous group of plant glycans in which a β1,3-galactan backbone and β1,6-galactan side chains are conserved. Diversity is provided by… read more here.
Keywords: degradation; side chains; bacteroides thetaiotaomicron; surface ... See more keywords
Phase-variable capsular polysaccharides and lipoproteins modify bacteriophage susceptibility in Bacteroides thetaiotaomicron
Sign Up to like & getrecommendations! Published in 2020 at "Nature microbiology"
DOI: 10.1038/s41564-020-0746-5
Abstract: A variety of cell surface structures dictate interactions between bacteria and their environment, including their viruses (bacteriophages). Members of the human gut Bacteroidetes characteristically produce several phase-variable capsular polysaccharides (CPSs), but their contributions to bacteriophage… read more here.
Keywords: polysaccharides lipoproteins; phase; variable capsular; bacteroides thetaiotaomicron ... See more keywords
Engineering dual-glycan responsive expression systems for tunable production of heterologous proteins in Bacteroides thetaiotaomicron
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-53726-w
Abstract: Genetically engineering intestinal bacteria, such as Bacteroides thetaiotaomicron (B. theta), holds potential for creating new classes of biological devices, such as diagnostics or therapeutic delivery systems. Here, we have developed a series of B. theta… read more here.
Keywords: engineering; glycan responsive; bacteroides thetaiotaomicron; dual glycan ... See more keywords
Ruminococcus bromii enables the growth of proximal Bacteroides thetaiotaomicron by releasing glucose during starch degradation.
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology"
DOI: 10.1099/mic.0.001180
Abstract: Complex carbohydrates shape the gut microbiota, and the collective fermentation of resistant starch by gut microbes positively affects human health through enhanced butyrate production. The keystone species Ruminococcus bromii (Rb) is a specialist in degrading… read more here.
Keywords: ruminococcus bromii; starch degradation; bacteroides thetaiotaomicron; degradation ... See more keywords
Lipidomics Analysis of Outer Membrane Vesicles and Elucidation of the Inositol Phosphoceramide Biosynthetic Pathway in Bacteroides thetaiotaomicron
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00634-21
Abstract: Sphingolipids are essential membrane lipid components found in eukaryotes that are also involved in cell signaling processes. Although rare in bacteria, sphingolipids are produced by members of the phylum “Bacteroidetes,” human gut commensals. Here, we… read more here.
Keywords: bt1522 1526; outer membrane; analysis; bacteroides thetaiotaomicron ... See more keywords
Investigation and Alteration of Organic Acid Synthesis Pathways in the Mammalian Gut Symbiont Bacteroides thetaiotaomicron
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DOI: 10.1128/spectrum.02312-21
Abstract: Both humans and animals host a large community of bacteria and other microorganisms in their gastrointestinal tracts. This community breaks down dietary fiber and produces organic acids that are used as an energy source by… read more here.
Keywords: acid synthesis; gut; organic acids; bacteroides thetaiotaomicron ... See more keywords