Cerebrospinal fluid biomarkers implicated in the pathogenesis of anti-neutrophil cytoplasmic antibody-related hypertrophic pachymeningitis
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DOI: 10.1007/s10067-020-04971-2
Abstract: Objective Hypertrophic pachymeningitis (HP) related to anti-neutrophil cytoplasmic antibody (ANCA) is the most frequently seen immune-mediated HP. We investigated cerebrospinal fluid (CSF) biomarkers related to the pathogenesis of ANCA-related HP (ANCA-HP). Methods The levels of… read more here.
Keywords: implicated pathogenesis; hypertrophic pachymeningitis; baff april; csf ... See more keywords
A BAFF/APRIL axis regulates obesogenic diet-driven weight gain
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DOI: 10.1038/s41467-021-23084-1
Abstract: The impact of immune mediators on weight homeostasis remains underdefined. Interrogation of resistance to diet-induced obesity in mice lacking a negative regulator of Toll-like receptor signaling serendipitously uncovered a role for B cell activating factor… read more here.
Keywords: april axis; baff; weight gain; baff april ... See more keywords
Maternal and cord blood BAFF and APRIL levels during pregnancy
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DOI: 10.1111/aji.13654
Abstract: Dysregulation of factors vital to the survival B cells and/or plasma cells, such as BAFF and APRIL, could be detrimental to a pregnancy. read more here.
Keywords: april levels; blood baff; cord blood; april ... See more keywords
BAFF inhibition in SLE—Is tolerance restored?
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DOI: 10.1111/imr.12810
Abstract: The B cell activating factor (BAFF) inhibitor, belimumab, is the first biologic drug approved for the treatment of SLE, and exhibits modest, but durable, efficacy in decreasing disease flares and organ damage. BAFF and its… read more here.
Keywords: inhibition sle; baff april; inhibition; baff inhibition ... See more keywords
The relationship between serum A proliferation-inducing ligand and B-cell activating factor levels with disease activity and organ involvement in systemic lupus erythematosus
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DOI: 10.1177/09612033221086123
Abstract: Objectives We aim to investigate the association between serum B-cell activating factor (BAFF) and A proliferation-inducing ligand (APRIL) levels with disease activity and clinical findings in SLE patients. Methods Seventy-nine patients with SLE and 27… read more here.
Keywords: disease activity; april; april levels; baff april ... See more keywords
Subclinical Atherosclerosis Is Associated with Discrepancies in BAFF and APRIL Levels and Altered Breg Potential of Precursor-like Marginal Zone B-Cells in Long-Term HIV Treated Individuals
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DOI: 10.3390/vaccines11010081
Abstract: Chronic inflammation persists in people living with HIV (PLHIV) despite antiretrovial therapy (ART), and is involved in their premature development of cardiovascular diseases (CVD) such as atherosclerosis. We have previously reported that an excess of… read more here.
Keywords: april levels; hiv; treated individuals; marginal zone ... See more keywords