Methotrexate and BAFF interaction prevents immunization against TNF inhibitors
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DOI: 10.1136/annrheumdis-2018-213403
Abstract: Objectives TNF inhibitors (TNFi) can induce anti-drug antibodies (ADA) in patients with autoimmune diseases (AID) leading to clinical resistance. We explored a new way of using methotrexate (MTX) to decrease this risk of immunisation. Methods… read more here.
Keywords: tnfi; baff; bafftg mice; mtx ... See more keywords