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   Articles with "bag2" as a keyword



c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro.

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recommendations! Published in 2022 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2022.03.138

Abstract: Deubiquitinases (DUBs) play critical roles in tumorigenesis and are emerging as potential therapeutic targets. However, it remains less clear which DUBs may play important roles and represent a realistic vulnerability for a particular type of… read more here.

Keywords: bag2; bag2 axis; myc usp49; usp49 bag2 ... See more keywords

Bag2 Is a Component of a Cytosolic Extraction Machinery That Promotes Membrane Penetration of a Nonenveloped Virus

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recommendations! Published in 2018 at "Journal of Virology"

DOI: 10.1128/jvi.00607-18

Abstract: ABSTRACT During entry, the nonenveloped polyomavirus (PyV) simian virus 40 (SV40) traffics from the cell surface to the endoplasmic reticulum (ER), where it penetrates the ER membrane to reach the cytosol; the virus is then… read more here.

Keywords: nonenveloped virus; extraction machinery; bag2; infection ... See more keywords

BAG2-activated cell autophagy and mir-27b dynamic regulation mechanism during Mycobacterium tuberculosis infection.

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recommendations! Published in 2022 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2021.67.5.5

Abstract: Tuberculosis is a highly contagious infectious disease. Mycobacterium tuberculosis infection is the main cause of tuberculosis. During the infection of M. tuberculosis, the expression of the resistance gene BAG2 will change, and miR-27b will play… read more here.

Keywords: tuberculosis; cell autophagy; tuberculosis infection; bag2 ... See more keywords

Targeting the BAG2/CHIP axis promotes gastric cancer apoptosis by blocking apoptosome assembly

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recommendations! Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1578416

Abstract: Apoptosis has been shown to play an important role in the treatment of gastric cancer, and BCL2-associated athanogene 2(BAG2) has been found to be able to inhibit apoptosis by interacting with multiple apoptosis regulators. In… read more here.

Keywords: apoptosis blocking; bag2; gastric cancer; chip ... See more keywords
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Metastasis Risk Assessment Using BAG2 Expression by Cancer-Associated Fibroblast and Tumor Cells in Patients with Breast Cancer

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recommendations! Published in 2021 at "Cancers"

DOI: 10.3390/cancers13184654

Abstract: Simple Summary Cancer-associated fibroblasts (CAFs) promote tumor progression and play an important role in evading immune surveillance. The previous study showed that BAG2 could be elevated in cancer associated fibroblasts (CAFs). Here, we evaluated BAG2… read more here.

Keywords: cancer; bag2; bag2 expression; tumor cells ... See more keywords