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   Articles with "bai1" as a keyword



Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development

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recommendations! Published in 2022 at "Experimental Neurology"

DOI: 10.1016/j.expneurol.2022.113994

Abstract: The adhesion G protein-coupled receptor BAI1/ADGRB1 plays an important role in suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor. BAI1 is also a critical regulator of dendritic spine and excitatory synapse development… read more here.

Keywords: seizure susceptibility; adgrb1; mice; full length ... See more keywords

LncRNA embryonic stem cells expressed 1 (Lncenc1) is identified as a novel regulator in neuropathic pain by interacting with EZH2 and downregulating the expression of BAI1 in mouse microglia.

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recommendations! Published in 2020 at "Experimental cell research"

DOI: 10.1016/j.yexcr.2020.112435

Abstract: LncRNA embryonic stem cells expressed 1 (Lncenc1), named after its high expression in naïve embryonic stem cells (nESCs), has been rarely studied in almost all pathological processes. Evidences suggest that Lncenc1 is likely to work… read more here.

Keywords: bai1; lncenc1; ezh2; expression ... See more keywords

CSIG-17. ADHESION GPCR BAI1/ADGRB1 CAN BLOCK IGF1R-MEDIATED GROWTH SIGNALLING, INCREASE RADIOSENSITIVITY AND AUGMENT SURVIVAL IN MEDULLOBLASTOMA

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae165.0266

Abstract: Medulloblastoma (MB) is an aggressive pediatric brain tumors and increased knowledge about the disease mechanisms is needed to develop new therapeutic approaches. Brain-specific Angiogenesis Inhibitor 1 (BAI1/ADGRB1) is an adhesion GPCR receptor and tumor suppressor… read more here.

Keywords: bai1; bai1 adgrb1; adhesion gpcr; medulloblastoma ... See more keywords

Abstract 4291: Bai1 inhibition promotes ferroptosis of breast cancer cells to prevent tumor growth in human xenograft tumor models

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recommendations! Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-4291

Abstract: The adhesion G-protein coupled- receptor 1 ADGRB1/Bai1 was identified as a phosphatidylserine receptor that cooperates with ELMO/Dock180/Rac to promote maximal engulfment of apoptotic cells. This function of Bai1 was also shown to promote myoblasts fusion.… read more here.

Keywords: bai1; cancer; breast cancer; breast ... See more keywords

BAI1 as a Prognostic Marker of Clear Cell Renal Cell Carcinoma (ccRCC)

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recommendations! Published in 2021 at "AntiCancer Research"

DOI: 10.21873/anticanres.15255

Abstract: Background/Aim: The treatment of advanced clear cell renal cell carcinoma (ccRCC) is based on stratification of patients according to prognosis (favorable, intermediate, and poor). The aim of the study was to improve prognostication by biomarkers… read more here.

Keywords: bai1; ccrcc; cell carcinoma; expression ... See more keywords