Develop a stepwise integrated method to screen biomarkers of Baihe-Dihuang Tang on the treatment of depression in Rats Applying with composition screened, untargeted and targeted metabolomics analysis.
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DOI: 10.1002/jssc.202100841
Abstract: Baihe-Dihuang Tang is a commonly prescribed remedy for depression. In this study, component screening with untargeted and targeted metabolomics was used to to identify potential biomarkers for depression in chronic unpredictable mildly-stressed rats. Using this… read more here.
Keywords: baihe dihuang; depression; targeted metabolomics; dihuang tang ... See more keywords
Systematic Analysis of Chemical Constituents and Pharmacokinetics of Baihe Dihuang Decoction In Vivo by UHPLC-MS/MS.
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DOI: 10.1002/jssc.70281
Abstract: Baihe Dihuang decoction (BDD), composed of Lilii Bulbus and Rehmanniae Radix, is a classical Chinese herbal formula. It demonstrates clinical applications in treating emotional disorders and anxiety. In this study, we characterized the chemical basis… read more here.
Keywords: vivo; chemical constituents; dihuang decoction; baihe dihuang ... See more keywords