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Bax and Bak Pores: Are We Closing the Circle?

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0 Published in 2017 at "Trends in cell biology"

DOI: 10.1016/j.tcb.2016.11.004

Abstract: Bax and its homolog Bak are key regulators of the mitochondrial pathway of apoptosis. On cell stress Bax and Bak accumulate at distinct foci on the mitochondrial surface where they undergo a conformational change, oligomerize,… read more here.

Keywords: pores closing; closing circle; bak pores; bak ... See more keywords