BAL fluid analysis in the identification of infectious agents in patients with hematological malignancies and pulmonary infiltrates
Sign Up to like & getrecommendations! Published in 2019 at "Folia Microbiologica"
DOI: 10.1007/s12223-019-00712-4
Abstract: The present study aims to evaluate the diagnostic yield of bronchoalveolar lavage (BAL) fluid in patients with hematological malignancies and describe the most common pathogens detected in BAL fluid (BALF.) An analysis of 480 BALF… read more here.
Keywords: patients hematological; fluid; hematological malignancies; pulmonary infiltrates ... See more keywords
Toxicological implication of prostaglandin transporter SLCO2A1 inhibition by cigarette smoke in exacerbation of lung inflammation.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115201
Abstract: We reported that bleomycin (BLM)-induced pulmonary fibrosis was exacerbated in the prostaglandin transporter gene (Slco2a1)-deficient mice (Slco2a1(-/-)). Because cigarette smoke (CS) contributes to creating a profibrotic milieu in the respiratory region, the present study aimed… read more here.
Keywords: cigarette smoke; bal fluid; inflammation; slco2a1 ... See more keywords
Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties
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DOI: 10.1038/s41598-020-59071-7
Abstract: Arginine residues of the antimicrobial peptide LL-37 can be citrullinated by peptidyl arginine deiminases, which reduce the positive charge of the peptide. Notably, citrullinated LL-37 has not yet been detected in human samples. In addition,… read more here.
Keywords: human airways; detection human; bal fluid; citrullinated detection ... See more keywords
IL-15 Superagonist N-803 Enhances IFN-γ Production of MAIT Cells in SIV+ Macaques
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Immunity"
DOI: 10.1128/iai.00259-22
Abstract: Mucosal associated invariant T (MAIT) cells are innate T cells that recognize bacterial metabolites and secrete cytokines and cytolytic enzymes to destroy infected target cells. This makes MAIT cells promising targets for immunotherapy to combat… read more here.
Keywords: superagonist 803; mait cells; mait; bacterial infections ... See more keywords
Retrospective Multicenter Evaluation of the VirClia Galactomannan Antigen Assay for the Diagnosis of Pulmonary Aspergillosis with Bronchoalveolar Lavage Fluid Samples from Patients with Hematological Disease
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.00044-23
Abstract: Galactomannan (GM) testing of bronchoalveolar lavage (BAL) fluid samples has become an essential tool to diagnose invasive pulmonary aspergillosis (IPA) and is part of diagnostic guidelines. Enzyme-linked immunosorbent assays (ELISAs) (enzyme immunoassays [EIAs]) are commonly… read more here.
Keywords: bronchoalveolar lavage; fluid; ipa; fluid samples ... See more keywords
Upregulation of Potassium Voltage-Gated Channel Subfamily J Member 2 Levels in the Lungs of Patients with Idiopathic Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2020 at "Canadian Respiratory Journal"
DOI: 10.1155/2020/3406530
Abstract: Background Fibroblast dysfunction is the main pathogenic mechanism underpinning idiopathic pulmonary fibrosis (IPF). Potassium voltage-gated channel subfamily J member 2 (KCNJ2) plays critical roles in the proliferation of myofibroblasts and in the development of cardiac… read more here.
Keywords: kcnj2 protein; ipf ipf; 001 kcnj2; ipf ... See more keywords
Insulin Rescues Diabetes-Induced Pulmonary Complications
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DOI: 10.2337/db18-454-p
Abstract: Hyperglycemia is an independent risk factor for the development of respiratory diseases, including influenza infections. Although the lung is a major organ to utilize glucose, the regulation of glucose transport in the healthy and diabetic… read more here.
Keywords: pulmonary complications; insulin rescues; none; diabetic mice ... See more keywords