First report of the isolation of Balamuthia mandrillaris in the northern region of Japan
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology Research"
DOI: 10.1007/s00436-018-5980-x
Abstract: Balamuthia mandrillaris is a free-living amoeba that lives in soil and water near human settlements. B. mandrillaris was first isolated from a mandrill baboon that died at the San Diego Zoo Wildlife Park in California… read more here.
Keywords: balamuthia mandrillaris; report isolation; japan; isolation balamuthia ... See more keywords
Diagnostic evaluation of fatal Balamuthia mandrillaris meningoencephalitis in a captive Bornean orangutan (Pongo pygmaeus) with identification of potential environmental source and evidence of chronic exposure
Sign Up to like & getrecommendations! Published in 2020 at "Primates"
DOI: 10.1007/s10329-020-00860-z
Abstract: A female Bornean orangutan ( Pongo pygmaeus ) aged 11 years and 6 months was examined by veterinarians after caretakers observed lethargy and facial grimacing. Within 72Â h the primate had left-sided hemiparesis that worsened over… read more here.
Keywords: bornean orangutan; balamuthia mandrillaris; pongo pygmaeus; orangutan pongo ... See more keywords
Balamuthia mandrillaris granulomatous amoebic encephalitis: The first African experience.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piac096
Abstract: We report the first case of Balamuthia mandrillaris granulomatous amoebic encephalitis definitively acquired in Africa. Our case emphasises initial non-specific dermatological features, delays in confirmation of the diagnosis, difficulties accessing recommended medication, and uncertainty about… read more here.
Keywords: balamuthia mandrillaris; granulomatous amoebic; first african; amoebic encephalitis ... See more keywords
Balamuthia mandrillaris-Related Primary Amoebic Encephalitis in China Diagnosed by Next Generation Sequencing and a Review of the Literature.
Sign Up to like & getrecommendations! Published in 2019 at "Laboratory medicine"
DOI: 10.1093/labmed/lmz079
Abstract: BACKGROUND Encephalitis is caused by infection, immune mediated diseases, or primary inflammatory diseases. Of all the causative infectious pathogens, 90% are viruses or bacteria. Granulomatous amoebic encephalitis (GAE), caused by Balamuthia mandrillaris, is a rare… read more here.
Keywords: next generation; generation sequencing; amoebic encephalitis; balamuthia mandrillaris ... See more keywords
Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen Balamuthia mandrillaris
Sign Up to like & getrecommendations! Published in 2018 at "mBio"
DOI: 10.1128/mbio.02051-18
Abstract: Balamuthia mandrillaris is responsible for hundreds of reported cases of amoebic encephalitis, the majority of which have been fatal. Despite being an exceptionally deadly pathogen, B. mandrillaris is understudied, leaving many open questions regarding epidemiology,… read more here.
Keywords: balamuthia mandrillaris; treatment; mandrillaris infections; nitroxoline ... See more keywords
An Optical and Chemiluminescence Assay for Assessing the Cytotoxicity of Balamuthia mandrillaris against Human Neurospheroids
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9070330
Abstract: A spheroid is a cell aggregate in a three-dimensional context; thereby, it recapitulates the cellular architecture in human tissue. However, the utility of spheroids as an assay for host–parasite interactions remains unexplored. This study demonstrates… read more here.
Keywords: balamuthia mandrillaris; mandrillaris; assessing cytotoxicity; optical chemiluminescence ... See more keywords
Discovery of Anti-Amoebic Inhibitors from Screening the MMV Pandemic Response Box on Balamuthia mandrillaris, Naegleria fowleri, and Acanthamoeba castellanii
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens"
DOI: 10.3390/pathogens9060476
Abstract: Pathogenic free-living amoebae, Balamuthia mandrillaris, Naegleria fowleri, and several Acanthamoeba species are the etiological agents of severe brain diseases, with case mortality rates > 90%. A number of constraints including misdiagnosis and partially effective treatments… read more here.
Keywords: balamuthia mandrillaris; response; castellanii; anti amoebic ... See more keywords
Amoebic Encephalitis Caused by Balamuthia mandrillaris
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pathology and Translational Medicine"
DOI: 10.4132/jptm.2019.05.14
Abstract: We present the case of a 71-year-old man who was diagnosed with amoebic encephalitis caused by Balamuthia mandrillaris. He had rheumatic arthritis for 30 years and had undergone continuous treatment with immunosuppressants. First, he complained… read more here.
Keywords: balamuthia mandrillaris; amoebic encephalitis; encephalitis; caused balamuthia ... See more keywords