The Baldwin Rearrangement: Synthesis of 2‐Acylaziridines
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700920
Abstract: The Baldwin rearrangement is a thermally induced ring contraction of 4-isoxazolines into 2-acylaziridines. The reaction yields highly strained nitrogen-containing three-membered-ring compounds from readily available five-membered N-O heterocycles. Diversely substituted isoxazolines are directly transformed into a… read more here.
Keywords: chemistry; rearrangement synthesis; synthesis acylaziridines; baldwin rearrangement ... See more keywords
Highly Stereoselective Synthesis of New Aziridines via Baldwin Rearrangement and Their Potential Biological Activities
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Heterocyclic Chemistry"
DOI: 10.1002/jhet.2548
Abstract: An atom-economical conversion of N-substituted isoxazoline derivatives to new N-substituted aziridines has been described using microwave irradiation through Baldwin rearrangement. N-substituted isoxazoline derivatives have been synthesized using a variety of nitrones and alkynes via 1,3-dipolar… read more here.
Keywords: highly stereoselective; synthesis new; stereoselective synthesis; baldwin rearrangement ... See more keywords