Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00026
Abstract: Balkan endemic nephropathy (BEN) is a multifactorial environmental disease, with chronic exposure to aristolochic acids (AAs) through AA-contaminated food being one of the major etiological mechanisms. However, the bulk of previous research has only focused… read more here.
Keywords: balkan endemic; adduct formation; etiology; dna adduct ... See more keywords
Effects of Heavy Metal Co-Exposure on the formation of DNA Adducts from Aristolochic Acid I: Implications for Balkan Endemic Nephropathy Development.
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DOI: 10.1021/acs.chemrestox.4c00045
Abstract: Accumulated evidence has shown that Balkan endemic nephropathy (BEN) is a multifactorial environmental disease, with exposure to aristolochic acids (AA), and the associated DNA adduct formation, as a key causative factor of BEN development. Here,… read more here.
Keywords: balkan endemic; formation dna; endemic nephropathy; exposure ... See more keywords
Arterial Stiffness in Balkan Endemic Nephropathy, an Environmental Form of Aristolochic Acid Nephropathy
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DOI: 10.3389/fcvm.2018.00166
Abstract: Balkan endemic nephropathy (BEN), an environmental form of aristolochic acid nephropathy is characterized with later onset and milder forms of hypertension (HT). Thus, we hypothesized that arterial stiffness progresses slower in BEN patients resulting in… read more here.
Keywords: environmental form; ben; balkan endemic; ben patients ... See more keywords
Predictive Markers for Malignant Urothelial Transformation in Balkan Endemic Nephropathy: A Case–Control Study
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DOI: 10.3390/cancers12102945
Abstract: Simple Summary Balkan endemic nephropathy (BEN) is chronic kidney disease caused by intoxication with Aristolochia plant. Apart from subtle decline of renal function that eventually results in kidney failure, the patients are at increased risk… read more here.
Keywords: ben; balkan endemic; study; ben patients ... See more keywords
Assessment of Retinal Microangiopathy in Patients with Balkan Endemic Nephropathy Using Optical Coherence Tomography Angiography—A Pilot Study
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DOI: 10.3390/medicina60010192
Abstract: Background and Objectives: It is well known that alterations in microvascular structure and function contribute to the development of ocular, renal, and cardiovascular diseases. Accordingly, the presence of fundus vascular changes in patients suffering from… read more here.
Keywords: optical coherence; balkan endemic; endemic nephropathy; group ... See more keywords
Biological Activity and NMR-Fingerprinting of Balkan Endemic Species Stachys thracica Davidov
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DOI: 10.3390/metabo12030251
Abstract: Stachys thracica Davidov is a Balkan endemic species distributed in Bulgaria, Greece, and Turkey. In Bulgaria, it is classified as “rare” and is under the protection of the Bulgarian biodiversity law. The aim of our… read more here.
Keywords: vitro; balkan endemic; thracica; thracica davidov ... See more keywords
Urine Metabolomic Signature of People Diagnosed with Balkan Endemic Nephropathy and Other Types of Chronic Kidney Disease Compared with Healthy Subjects in Romania
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DOI: 10.3390/metabo13050609
Abstract: Metabolomic analysis methods were employed to determine biomarkers for various chronic kidney diseases (CKDs). Modern analytical methods were developed and applied successfully to find a specific metabolomic profile in urine samples from CKD and Balkan… read more here.
Keywords: balkan endemic; urine samples; chronic kidney; analysis ... See more keywords