The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2022.114948
Abstract: Acute myeloid leukemia (AML) is a malignant proliferative disease of myeloid hematopoietic origin and cannot be treated appropriately at present. This is due to the fact that leukemia cells are not sensitive to some of… read more here.
Keywords: ros production; acute myeloid; bam15; myeloid leukemia ... See more keywords
Abstract 4687: Primary study on the anticancer role of BAM15 in lung cancer cells
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-4687
Abstract: Background: Lung cancer remains the leading cause of cancer-related death worldwide. Non-small cell lung cancer (NSCLC) accounts for about 80-85% of all lung cancer cases. BAM15, a mitochondrial uncoupler, is a potential therapeutic agent for… read more here.
Keywords: cancer; lung cancer; bam15; nsclc cells ... See more keywords