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Published in 2017 at "Journal of Molecular Biology"
DOI: 10.1016/j.jmb.2017.09.008
Abstract: The biogenesis of outer-membrane proteins (OMPs) in gram-negative bacteria involves delivery by periplasmic chaperones to the β-barrel assembly machinery (BAM), which catalyzes OMP insertion into the outer membrane. Here, we examine the effects of membrane…
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Keywords:
periplasmic chaperones;
barrel;
bama;
outer membrane ... See more keywords
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Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.02.023
Abstract: The β-barrel assembly machine (BAM) integrates β-barrel proteins into the outer membrane (OM) of Gram-negative bacteria. An essential BAM subunit (BamA) catalyzes integration by promoting the formation of a hybrid-barrel intermediate state between its own…
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Keywords:
polypeptide export;
barrel;
bama;
outer membrane ... See more keywords
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Published in 2023 at "Membranes"
DOI: 10.3390/membranes13020247
Abstract: Transmembrane proteins span lipid bilayer membranes and serve essential functions in all living cells. Membrane-inserted domains are of either α-helical or β-barrel structure. Despite their biological importance, the biophysical mechanisms of the folding and insertion…
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Keywords:
spectroscopy;
form;
folding insertion;
bama ... See more keywords