Transcriptomic analysis revealing hepcidin expression in Oryzias melastigma regulated through the JAK-STAT signaling pathway upon exposure to BaP.
Sign Up to like & getrecommendations! Published in 2019 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2018.11.015
Abstract: Our previous study revealed that an antimicrobial peptide hepcidin, can be significantly up-regulated either with LPS challenge or upon exposure to Benzo[a]pyrene (BaP) in red sea bream, but the molecular mechanism involved in whether the… read more here.
Keywords: lps challenge; exposure; jak stat; bap exposure ... See more keywords
Exposure to benzo(a)pyrene from juvenile period to peripubertal impairs male reproductive parameters in adult rats.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.128016
Abstract: Benzo(a)pyrene (BaP) is a persistent organic pollutant and endocrine disruptor that can compromise the steroidogenesis process by interacting with the StAR protein, causing adverse effects on male reproduction. However, consequences of prepubertal BaP exposure and… read more here.
Keywords: benzo pyrene; bap exposure; juvenile period; exposure ... See more keywords
Benzo(a)pyrene exposure induced neuronal loss, plaque deposition, and cognitive decline in APP/PS1 mice
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01925-y
Abstract: Background Exposure to benzo(a)pyrene (BaP) was associated with cognitive impairments and some Alzheimer’s disease (AD)-like pathological changes. However, it is largely unknown whether BaP exposure participates in the disease progression of AD. Objectives To investigate… read more here.
Keywords: exposure; ps1 mice; bap exposure; mice ... See more keywords