Articles with "bap1 mutant" as a keyword



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BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

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Published in 2019 at "Science Advances"

DOI: 10.1126/sciadv.aax1738

Abstract: BAP1 regulates developmental switch in lineages commonly affected by BAP1-mutant cancers. The BAP1 tumor suppressor is mutated in many human cancers such as uveal melanoma, leading to poor patient outcome. It remains unclear how BAP1… read more here.

Keywords: mutant cancers; bap1 regulates; bap1; switch ... See more keywords