Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
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DOI: 10.3389/fonc.2023.1140730
Abstract: Introduction The leukemia inhibitory factor (LIF), is a cytokine belonging to IL-6 family, whose overexpression correlate with poor prognosis in cancer patients, including pancreatic ductal adenocarcinoma (PDAC). LIF signaling is mediate by its binding to… read more here.
Keywords: inhibitory factor; lif lifr; bar502; leukemia inhibitory ... See more keywords