SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108921
Abstract: SUMMARY The breast cancer type I susceptibility protein (BRCA1) and BRCA1-associated RING domain protein I (BARD1) heterodimer promote genome integrity through pleiotropic functions, including DNA double-strand break (DSB) repair by homologous recombination (HR). BRCA1-BARD1 heterodimerization… read more here.
Keywords: bard1 heterodimerization; brca1 bard1; sirt2;