β-barrel Oligomers as Common Intermediates of Peptides Self-Assembling into Cross-β Aggregates
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DOI: 10.1038/s41598-018-28649-7
Abstract: Oligomers populated during the early amyloid aggregation process are more toxic than mature fibrils, but pinpointing the exact toxic species among highly dynamic and heterogeneous aggregation intermediates remains a major challenge. β-barrel oligomers, structurally-determined recently… read more here.
Keywords: self assembling; barrel; barrel oligomers; peptides self ... See more keywords