Articles with "barrel stave" as a keyword



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The Perpendicular Orientation of Amphotericin B Methyl Ester in Hydrated Lipid Bilayers Supports the Barrel-Stave Model.

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Published in 2019 at "Biochemistry"

DOI: 10.1021/acs.biochem.9b00180

Abstract: The clinically important antibiotic amphotericin B (AmB) is a membrane-active natural product that targets membrane sterol. The antimicrobial activity of AmB is generally attributed to its membrane permeabilization, which occurs when a pore is formed… read more here.

Keywords: supports barrel; barrel stave; stave model; amb ... See more keywords