Efflux of TolC protein to different antimicrobials can be replaced by other outer membrane proteins with similar β-barrel structures in extraintestinal pathogenic Escherichia coli.
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DOI: 10.1093/jambio/lxae214
Abstract: AIM As a major efflux pump system in Gram-negative bacteria, AcrAB-TolC plays a key role in the transport of multiple drug substrates and is considered a potential target for the development of novel antimicrobials. Our… read more here.
Keywords: similar barrel; barrel structures; different antimicrobials; tolc ... See more keywords