Barrett's esophagus: The pathomorphological and molecular genetic keystones of neoplastic progression
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DOI: 10.1002/cam4.4447
Abstract: Barrett's esophagus is a widespread chronically progressing disease of heterogeneous nature. A life threatening complication of this condition is neoplastic transformation, which is often overlooked due to lack of standardized approaches in diagnosis, preventative measures… read more here.
Keywords: barrett; neoplastic progression; barrett esophagus; esophagus pathomorphological ... See more keywords
Diabetes in relation to Barrett’s esophagus and adenocarcinomas of the esophagus: A pooled study from the International Barrett’s and Esophageal Adenocarcinoma Consortium
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DOI: 10.1002/cncr.32444
Abstract: Diabetes is positively associated with various cancers, but its relationship with tumors of the esophagus/esophagogastric junction remains unclear. read more here.
Keywords: barrett esophagus; esophagus; relation barrett; barrett ... See more keywords
Towards improved endoscopic surveillance with Multidiameter Single Fiber Reflectance Spectroscopy in patients with Barrett's esophagus.
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DOI: 10.1002/jbio.202000351
Abstract: Patients with Barrett's esophagus are at an increased risk to develop esophageal cancer and, therefore, undergo regular endoscopic surveillance. Early detection of neoplasia enables endoscopic treatment, which improves outcomes. However, early Barrett's neoplasia is easily… read more here.
Keywords: barrett esophagus; surveillance; endoscopic surveillance; spectroscopy ... See more keywords
A new artificial intelligence system successfully detects and localises early neoplasia in Barrett's esophagus by using convolutional neural networks
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12233
Abstract: Abstract Background and aims Seattle protocol biopsies for Barrett's Esophagus (BE) surveillance are labour intensive with low compliance. Dysplasia detection rates vary, leading to missed lesions. This can potentially be offset with computer aided detection.… read more here.
Keywords: barrett esophagus; neural networks; intelligence system; cnn ... See more keywords
Barrett Esophagus: Quality of life and factors associated with illness perception
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DOI: 10.1002/ueg2.12266
Abstract: Abstract Background Health‐related Quality of life (HRQoL) in patients with Barrett's esophagus (BE), a premalignant condition, may be influenced by gastroesophageal reflux disease (GERD) symptoms and the risk of developing esophageal adenocarcinoma. Methods We aim… read more here.
Keywords: barrett esophagus; factors associated; expert centers; illness perception ... See more keywords
The Cellular Origin of Barrett's Esophagus and Its Stem Cells.
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DOI: 10.1007/978-3-030-11096-3_5
Abstract: The incidence of esophageal adenocarcinoma is rapidly increasing in Western countries. This is despite the introduction of sophisticated endoscopic techniques and our ability to readily monitor the presumed precursor lesion known as Barrett's esophagus. Preemptive… read more here.
Keywords: origin barrett; barrett esophagus; cellular origin; stem ... See more keywords
Targeted Hsp70 fluorescence molecular endoscopy detects dysplasia in Barrett’s esophagus
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DOI: 10.1007/s00259-021-05582-y
Abstract: The incidence of esophageal adenocarcinoma (EAC) has been increasing for decades without significant improvements in treatment. Barrett’s esophagus (BE) is best established risk factor for EAC, but current surveillance with random biopsies cannot predict progression… read more here.
Keywords: barrett esophagus; endoscopy; fluorescence molecular; hsp70 tpp ... See more keywords
Antireflux Surgery and Barrett’s Esophagus: Myth or Reality?
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DOI: 10.1007/s00268-017-4394-8
Abstract: BackgroundIt may seem questionable if antireflux surgery still has a role in the management of patients with Barrett’s esophagus (BE) in the current era when antireflux surgery is facing a steady decline, obesity is increasing,… read more here.
Keywords: surgery; barrett esophagus; antireflux surgery; gerd ... See more keywords
Gastroesophageal Reflux Disease Might Induce Certain—Supposedly Adaptive—Changes in the Esophagus: A Hypothesis
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DOI: 10.1007/s10620-018-5184-3
Abstract: BackgroundThe increasing prevalence of GERD has become a major concern due to its major health and economic impacts. Beyond the typical unpleasant symptoms, reflux can also be the source of severe, potentially life-threatening complications, such… read more here.
Keywords: esophageal; reflux; barrett esophagus; esophageal sphincter ... See more keywords
CDX-2 Expression in Esophageal Biopsies Without Goblet Cell Intestinal Metaplasia May Be Predictive of Barrett’s Esophagus
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05914-x
Abstract: Background CDX-2 is a nuclear homeobox transcription factor not normally expressed in esophageal and gastric epithelia, reported to highlight intestinal metaplasia (IM) in the esophagus. Pathological absence of goblet cells at initial screening via hematoxylin… read more here.
Keywords: intestinal metaplasia; barrett esophagus; goblet; cdx ... See more keywords
Role of Extracellular Vesicles in the Diagnosis and Pathogenesis of Barrett’s Esophagus: A Mini-Review
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DOI: 10.1007/s10620-020-06250-1
Abstract: Esophageal adenocarcinoma (EAC) continues to be a significant public health problem with survival rates that have remained stagnant. Although the population at the highest risk for EAC, i.e., patients with Barrett’s esophagus (BE) has been… read more here.
Keywords: extracellular vesicles; barrett esophagus; role extracellular; review ... See more keywords