CD80 expression promotes immune surveillance in Barrett’s metaplasia
Sign Up to like & getrecommendations! Published in 2019 at "Oncoimmunology"
DOI: 10.1080/2162402x.2019.1636618
Abstract: ABSTRACT Esophageal adenocarcinoma (EAC) is the final step of a pathway starting with esophageal reflux disease, Barrett’s metaplasia and Barrett’s dysplasia. Positive costimulatory ligands such as CD80 have been suggested to contribute to anti-tumor T-cell… read more here.
Keywords: barrett metaplasia; immune surveillance; cd80 expression; esophageal carcinogenesis ... See more keywords
p53 protein accumulation predicts malignant progression in Barrett's metaplasia: a prospective study of 275 patients
Sign Up to like & getrecommendations! Published in 2017 at "Histopathology"
DOI: 10.1111/his.13193
Abstract: The purpose of this study was to determine prospectively whether p53 protein accumulation in biopsies of Barrett's metaplasia (BM) is a predictor of malignant progression, without relying on dysplasia grading. read more here.
Keywords: p53 protein; study; barrett metaplasia; malignant progression ... See more keywords
Extensive telomere erosion is consistent with localised clonal expansions in Barrett’s metaplasia
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0174833
Abstract: Barrett’s oesophagus is a premalignant metaplastic condition that predisposes patients to the development of oesophageal adenocarcinoma. However, only a minor fraction of Barrett’s oesophagus patients progress to adenocarcinoma and it is thus essential to determine… read more here.
Keywords: extensive telomere; barrett metaplasia; erosion; telomere erosion ... See more keywords
Molecular endoscopic imaging for the detection of Barrett’s metaplasia using biodegradable inorganic nanoparticles: An ex-vivo pilot study on human tissue
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0239814
Abstract: Background and study aims Despite major technical advancements, endoscopic surveillance for detecting premalignant lesions in Barrett’s esophagus is challenging because of their flat appearance with only subtle morphological changes. Molecular endoscopic imaging (MEI) using nanoparticles… read more here.
Keywords: metaplasia; study; barrett metaplasia; molecular endoscopic ... See more keywords