Keratinocyte-derived IL-1β induces PPARG down-regulation and PPARD up-regulation in.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental dermatology"
DOI: 10.1111/exd.14323
Abstract: Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors. In skin, PPARs modulate inflammation, lipid synthesis, keratinocyte differentiation and proliferation and thus are important for skin barrier homeostasis. Accordingly, PPAR expression is altered… read more here.
Keywords: barrier; epidermal barrier; expression; barrier impairment ... See more keywords
Risk Factors for Intestinal Barrier Impairment in Patients With Essential Hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2020.543698
Abstract: Background: Previous studies have indicated an association between hypertension and intestinal barrier dysfunction in mice models. The present study aims to investigate the association between hypertension and intestinal barrier impairment in humans and identify the… read more here.
Keywords: barrier impairment; risk factors; hypertension; intestinal barrier ... See more keywords
Nanodelivery Strategies for Skin Diseases with Barrier Impairment: Focusing on Ceramides and Glucocorticoids
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DOI: 10.3390/nano12020275
Abstract: The human epidermis has a characteristic lipidic composition in the stratum corneum, where ceramides play a crucial role in the skin barrier homeostasis and in water-holding capacity. Several skin diseases, such as atopic dermatitis and… read more here.
Keywords: strategies skin; impairment focusing; skin diseases; diseases barrier ... See more keywords