Effects of benzoic acid, Bacillus coagulans and oregano oil combined supplementation on growth performance, immune status and intestinal barrier integrity of weaned piglets
Sign Up to like & getrecommendations! Published in 2020 at "Animal Nutrition"
DOI: 10.1016/j.aninu.2020.02.004
Abstract: This experiment was conducted to investigate the effects of benzoic acid, Bacillus coagulans and oregano oil combined supplementation on growth performance, immune status and intestinal barrier integrity of piglets. In a 26-d experiment, 25 piglets… read more here.
Keywords: immune status; intestinal barrier; barrier integrity; benzoic acid ... See more keywords
Clostridium butyricum relieves diarrhea by enhancing digestive function, maintaining intestinal barrier integrity, and relieving intestinal inflammation in weaned piglets
Sign Up to like & getrecommendations! Published in 2020 at "Livestock Science"
DOI: 10.1016/j.livsci.2020.104112
Abstract: Abstract The current study aimed to determine how Clostridium butyricum (C. butyricum) relieved diarrhea by evaluating its effects on intestinal digestive enzyme activity, barrier integrity, inflammatory responses, and oxidative stress in weaned piglets. A total… read more here.
Keywords: butyricum; barrier integrity; group; weaned piglets ... See more keywords
Sprayable Reactive Oxygen Species-Responsive Hydrogel Coatings Restore Endothelial Barrier Integrity for Functional Vascular Healing.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.5c05477
Abstract: Drug-coated balloons are advancing in coronary interventional therapy for stenosis but often cause traumatic vascular injury, leading to late-stage restenosis. A critical pathological event in this process is the early disruption of the endothelial barrier… read more here.
Keywords: endothelial barrier; integrity; reactive oxygen; barrier integrity ... See more keywords
Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity
Sign Up to like & getrecommendations! Published in 2020 at "Hypertension Research"
DOI: 10.1038/s41440-020-0528-8
Abstract: Preeclampsia (PE) is a pregnancy-related disorder characterized by hypertension and proteinuria that affects 3–10% of all pregnancies. Although its pathophysiology remains obscure, placental hypoxia-induced oxidative stress and alterations in vascular function, morphology, and endothelial barrier… read more here.
Keywords: hypoxia; barrier integrity; morphology; endothelial barrier ... See more keywords
Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00259-3
Abstract: In vitro models that better reflect in vivo epithelial barrier (patho-)physiology are urgently required to predict adverse drug effects. Here we introduce extracellular matrix-supported intestinal tubules in perfused microfluidic devices, exhibiting tissue polarization and transporter… read more here.
Keywords: membrane free; barrier integrity; time; free culture ... See more keywords
GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-021-03787-7
Abstract: GPR120 (encoded by FFAR4 gene) is a receptor for long chain fatty acids, activated by ω-3 Polyunsaturated Fatty Acids (PUFAs), and expressed in many cell types. Its role in the context of colorectal cancer (CRC)… read more here.
Keywords: mucosal barrier; gpr120; barrier integrity; progression ... See more keywords
Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by Angiotensin-(1-7).
Sign Up to like & getrecommendations! Published in 2023 at "Clinical science"
DOI: 10.1042/cs20220904
Abstract: Compromised barrier function of colon epithelium with aging is largely due to gut microbial dysbiosis. Recent studies implicate an important role for angiotensin converting enzymes, ACE and ACE2, angiotensins, and the receptors, AT1 receptor (AT1R)… read more here.
Keywords: gut; restructuring gut; gut microbiome; gut barrier ... See more keywords
A Direct Link Implicating Loss of SLC26A6 to Gut Microbial Dysbiosis, Compromised Barrier Integrity and Inflammation.
Sign Up to like & getrecommendations! Published in 2024 at "Gastroenterology"
DOI: 10.1053/j.gastro.2024.05.002
Abstract: BACKGROUND Putative anion transporter-1 (PAT1, SLC26A6) plays a key role in intestinal oxalate and bicarbonate secretion. PAT1 knockout (PKO) mice exhibit hyperoxaluria and nephrolithiasis. Notably, diseases such as inflammatory bowel diseases (IBD) are also associated… read more here.
Keywords: loss; pat1; integrity; inflammation ... See more keywords
ENTEROENDOCRINE CELLS REGULATE BARRIER INTEGRITY AND PROTECT AGAINST DSS-INDUCED OUTCOMES
Sign Up to like & getrecommendations! Published in 2025 at "Gastroenterology"
DOI: 10.1053/j.gastro.2025.01.150
Abstract: Enteroendocrine cells (EECs) are often dysregulated in metabolic and gastrointestinal diseases, such as inflammatory bowel disease, although their roles in disease pathogenesis remain unknown. EECs are rare sensory cells scattered throughout the gastrointestinal epithelium that… read more here.
Keywords: dss; cells regulate; enteroendocrine cells; regulate barrier ... See more keywords
Transverse aortic constriction impairs intestinal barrier integrity, promotes inflammation and alterations in gut microbiota composition
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.3667
Abstract: Microbiota composition plays an important role in the pathophysiology of heart failure (HF). Reduced cardiac output can disrupt intestinal barrier function and promote systemic inflammation through bacterial translocation. Several gut and cardiac pathological conditions are… read more here.
Keywords: barrier integrity; microbiota composition; intestinal barrier;
Microbiome-derived metabolite effects on intestinal barrier integrity and immune cell response to infection
Sign Up to like & getrecommendations! Published in 2024 at "Microbiology"
DOI: 10.1101/2024.02.06.579072
Abstract: The gut microbiota exerts a significant influence on human health and disease. While compositional changes in the gut microbiota in specific diseases can easily be determined, we lack a detailed mechanistic understanding of how these… read more here.
Keywords: metabolite effects; physiology; response infection; intestinal barrier ... See more keywords