Barriers to Drug Distribution into the Perinatal and Postnatal Brain
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DOI: 10.1007/s11095-018-2375-8
Abstract: Drug bioavailability to the developing brain is a major concern in the treatment of neonates and infants as well as pregnant and breast-feeding women. Central adverse drug reactions can have dramatic consequences for brain development,… read more here.
Keywords: blood brain; drug; drug distribution; brain ... See more keywords
Application of CRISPR-Cas9 System to Study Biological Barriers to Drug Delivery
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DOI: 10.3390/pharmaceutics14050894
Abstract: In recent years, sequence-specific clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) systems have been widely used in genome editing of various cell types and organisms. The most developed and broadly used CRISPR-Cas system, CRISPR-Cas9,… read more here.
Keywords: crispr cas9; barriers drug; crispr; application crispr ... See more keywords