Overcoming barriers in non-viral gene delivery for neurological applications.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr06939j
Abstract: Gene therapy for neurological disorders has attracted significant interest as a way to reverse or stop various disease pathologies. Typical gene therapies involving the central and peripheral nervous system make use of adeno-associated viral vectors… read more here.
Keywords: overcoming barriers; viral vectors; delivery; barriers non ... See more keywords
Beyond glycan barriers: non-cognate ligands and protein mimicry approaches to elicit broadly neutralizing antibodies for HIV-1
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-024-01073-y
Abstract: Human immunodeficiency virus type 1 (HIV-1) vaccine immunogens capable of inducing broadly neutralizing antibodies (bNAbs) remain obscure. HIV-1 evades immune responses through enormous diversity and hides its conserved vulnerable epitopes on the envelope glycoprotein (Env)… read more here.
Keywords: non cognate; broadly neutralizing; barriers non; beyond glycan ... See more keywords