Noninvasive Prenatal Detection of Hemoglobin Bart hydrops fetalis via maternal plasma dispensed with parental haplotyping using the Semiconductor Sequencing Platform (SSP).
Sign Up to like & getrecommendations! Published in 2019 at "American journal of obstetrics and gynecology"
DOI: 10.1016/j.ajog.2019.07.044
Abstract: BACKGROUND Thalassemia is one of most common monogenetic diseases in the south of China and Southeast Asia. Hemoglobin Bart's hydrops fetalis syndrome was caused by a homozygous SEA deletion (--/--) in the HBA gene. Few… read more here.
Keywords: hemoglobin bart; bart hydrops; maternal plasma; hydrops fetalis ... See more keywords
Optimizing transfusion therapy for survivors of Haemoglobin Bart's hydrops fetalis syndrome: Defining the targets for haemoglobin-H fraction and "functional" haemoglobin level.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of haematology"
DOI: 10.1111/bjh.18077
Abstract: Owing to the unique pathophysiology of anaemia in haemoglobin Bart's hydrops fetalis (HBHF), a transfusion strategy based on beta-thalassemia guidelines is suboptimal for chronically transfused HBHF patients. A more aggressive transfusion aimed at reducing the… read more here.
Keywords: haemoglobin bart; hydrops fetalis; bart hydrops; transfusion ... See more keywords
Outcomes of allogeneic transplantation for hemoglobin Bart’s hydrops fetalis syndrome in Hong Kong
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Transplantation"
DOI: 10.1111/petr.14037
Abstract: Hemoglobin Bart's hydrops fetalis syndrome (BHFS) was once considered a fatal condition universally. Medical advances over the past three decades have resulted in increasing numbers of BHFS survivors. This retrospective review summarized local territory‐wide experience… read more here.
Keywords: fetalis syndrome; bart hydrops; hong kong; hydrops fetalis ... See more keywords