A Novel Alternate Dosing of Vismodegib for Treatment of Patients With Advanced Basal Cell Carcinomas
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2016.5058
Abstract: A Novel Alternate Dosing of Vismodegib for Treatment of Patients With Advanced Basal Cell Carcinomas Basal cell carcinoma (BCC) is the most common cutaneous malignancy with a favorable prognosis, as the estimated cure rate when… read more here.
Keywords: dosing vismodegib; patients advanced; basal; basal cell ... See more keywords
Inherited Basaloid Neoplasms Associated With SUFU Pathogenic Variants.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2024.3315
Abstract: Importance Germline SUFU pathogenic variants (PVs) have previously been associated with basal cell nevus syndrome (BCNS) and multiple infundibulocystic basal cell carcinoma syndrome; however, a broader spectrum of cutaneous findings in patients with SUFU PVs… read more here.
Keywords: basal cell; sufu pvs; dermatology; basal ... See more keywords
Physical Conditions of Fast Glacier Flow: 2. Variable Extent of Anisotropic Ice and Soft Basal Sediment From Seismic Reflection Data Acquired on Store Glacier, West Greenland
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Geophysical Research"
DOI: 10.1002/2017jf004297
Abstract: Outlet glaciers of the Greenland Ice Sheet transport ice from the interior to the ocean and contribute directly to sea level rise because because discharge and ablation often exceed the accumulation. To develop a better… read more here.
Keywords: basal; west greenland; store glacier; reflection ... See more keywords
Cytological investigation of a first case of basal cell adenocarcinoma arising in the minor salivary glands. Case report and review of the literature
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.23919
Abstract: Basal cell adenocarcinoma (BCAC) of salivary glands is uncommon low‐grade malignancy. Only 19 cases of preoperative cytology were reported up to date. We present here a new case of BCAC arising in the minor salivary… read more here.
Keywords: arising minor; minor salivary; basal; case ... See more keywords
Perfoliate leaves reduce herbivory in the shield‐bracted monkeyflower ( Mimulus glaucescens )
Sign Up to like & getrecommendations! Published in 2022 at "Ecology"
DOI: 10.1002/ecy.3876
Abstract: Many plant species have leaves that are completely fused around the stem, forming a disk or cup, a trait called perfoliation (Appendix S1: Figure S1). This morphology has long fascinated naturalists (Beal & St. John,… read more here.
Keywords: damage; basal; leaf; plant ... See more keywords
Bidirectional regulation by “star forces”: Ionotropic astrocyte's optical stimulation suppresses synaptic plasticity, metabotropic one strikes back
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23486
Abstract: The role of astrocytes in modulating synaptic plasticity is an important question that until recently was not addressed due to limitations of previously existing technology. In the present study, we took an advantage of optogenetics… read more here.
Keywords: opto a1ar; depression; basal; stimulation ... See more keywords
Basal biomarkers nestin and INPP4B predict gemcitabine benefit in metastatic breast cancer: Samples from the phase III SBG0102 clinical trial
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.31969
Abstract: In a formal prospective‐retrospective analysis of the phase III SBG0102 clinical trial randomizing metastatic breast cancer patients to gemcitabine‐docetaxel or to single agent docetaxel, patients with basal‐like tumors by PAM50 gene expression had significantly better… read more here.
Keywords: basal; phase iii; nestin inpp4b; breast cancer ... See more keywords
Biobanked tracheal basal cells retain the capacity to differentiate
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.925
Abstract: While airway epithelial biorepositories have established roles in the study of bronchial progenitor stem (basal) cells, the utility of a bank of tracheal basal cells from pediatric patients, who have or are suspected of having… read more here.
Keywords: basal cells; retain capacity; tracheal basal; biobanked tracheal ... See more keywords
14‐3‐3σ/Stratifin and p21 limit AKT‐related malignant progression in skin carcinogenesis following MDM2‐associated p53 loss
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23771
Abstract: To study mechanisms driving/inhibiting skin carcinogenesis, stage‐specific expression of 14‐3‐3σ (Stratifin) was analyzed in skin carcinogenesis driven by activated rasHa/fos expression (HK1.ras/fos) and ablation of PTEN‐mediated AKT regulation (K14.creP/Δ5PTENflx/flx). Consistent with 14‐3‐3σ roles in epidermal… read more here.
Keywords: loss; basal; progression; carcinogenesis ... See more keywords
Oscillatory activity in the basal ganglia and deep brain stimulation
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.26714
Abstract: Over the past 10 years, research into the neurophysiology of the basal ganglia has provided new insights into the pathophysiology of movement disorders. The presence of pathological oscillations at specific frequencies has been linked to… read more here.
Keywords: basal; stimulation; activity basal; oscillatory activity ... See more keywords
A Proposed Circuit Computation in Basal Ganglia: History‐Dependent Gain
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27321
Abstract: In this Scientific Perspectives we first review the recent advances in our understanding of the functional architecture of basal ganglia circuits. Then we argue that these data can best be explained by a model in… read more here.
Keywords: basal; dependent gain; history dependent; basal ganglia ... See more keywords