NCS‐1 expression is higher in basal breast cancers and regulates calcium influx and cytotoxic responses to doxorubicin
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DOI: 10.1002/1878-0261.12589
Abstract: Neuronal calcium sensor‐1 (NCS‐1) is a positive modulator of IP3 receptors and was recently associated with poorer survival in breast cancers. However, the association between NCS‐1 and breast cancer molecular subtypes and the effects of… read more here.
Keywords: basal breast; breast; breast cancer; breast cancers ... See more keywords
ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
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DOI: 10.1038/s41388-021-02017-8
Abstract: ISG15 is an ubiquitin-like modifier that is associated with reduced survival rates in breast cancer patients. The mechanism by which ISG15 achieves this however remains elusive. We demonstrate that modification of Rab GDP-Dissociation Inhibitor Beta… read more here.
Keywords: basal breast; isgylation; egfr recycling; tumour progression ... See more keywords