Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses
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DOI: 10.1038/s41564-019-0425-6
Abstract: Current models of cell-intrinsic immunity to RNA viruses centre on virus-triggered inducible antiviral responses initiated by RIG-I-like receptors or Toll-like receptors that sense pathogen-associated molecular patterns, and signal downstream through interferon regulatory factors (IRFs), transcription… read more here.
Keywords: basal expression; rna viruses; interferon regulatory; rna ... See more keywords