Imaging gradual neurodegeneration in a basal ganglia model disease
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25566
Abstract: X‐linked dystonia‐parkinsonism (XDP) is a neurodegenerative disease with adult onset dystonia and subsequent parkinsonism. Postmortem and imaging studies revealed remarkable striatal pathology, with a predominant involvement of the striosomal compartment in the early phase. Here,… read more here.
Keywords: imaging gradual; gradual neurodegeneration; neurodegeneration basal; disease ... See more keywords
Basal Ganglia Atrophy as a Marker for Prodromal X‐Linked Dystonia‐Parkinsonism
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26606
Abstract: In neurodegenerative diseases, the characterization of the prodromal phase is essential for the future application of disease‐modifying therapies. X‐linked dystonia‐parkinsonism is a hereditary neurodegenerative movement disorder characterized by severe adult‐onset dystonia accompanied by parkinsonism. Distinct… read more here.
Keywords: dystonia parkinsonism; non manifesting; linked dystonia; parkinsonism ... See more keywords
Basal ganglia dysplasia and mTORopathy: A potential cause of postoperative seizures in focal cortical dysplasia
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12678
Abstract: Pathogenic somatic MTOR variants in the cerebral cortex are a frequent cause of focal cortical dysplasia (FCD). We describe a child with drug and surgery‐resistant focal epilepsy due to FCD type II who developed progressive… read more here.
Keywords: cause; cortical dysplasia; dysplasia; basal ganglia ... See more keywords
White matter degeneration in remote brain areas of stroke patients with motor impairment due to basal ganglia lesions
Sign Up to like & getrecommendations! Published in 2021 at "Human Brain Mapping"
DOI: 10.1002/hbm.25583
Abstract: Diffusion tensor imaging (DTI) studies have revealed distinct white matter (WM) characteristics of the brain following diseases. Beyond the lesion‐symptom maps, stroke is characterized by extensive structural and functional alterations of brain areas remote to… read more here.
Keywords: brain areas; stroke patients; brain; basal ganglia ... See more keywords
RGS14 expression in CA2 hippocampus, amygdala, and basal ganglia: Implications for human brain physiology and disease
Sign Up to like & getrecommendations! Published in 2022 at "Hippocampus"
DOI: 10.1002/hipo.23492
Abstract: RGS14 is a multifunctional scaffolding protein that is highly expressed within postsynaptic spines of pyramidal neurons in hippocampal area CA2. Known roles of RGS14 in CA2 include regulating G protein, H‐Ras/ERK, and calcium signaling pathways… read more here.
Keywords: basal ganglia; rgs14 expression; physiology; ca2 ... See more keywords
Neutrophil‐to‐Lymphocyte ratio on admission predicts gastrointestinal bleeding in acute basal ganglia hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24679
Abstract: Gastrointestinal bleeding (GIB) is a potential contributing factor for poor prognosis of spontaneous basal ganglia hemorrhage (BGH). This study aimed to investigate the predictive value of new inflammatory biomarkers including neutrophil to lymphocytes (NLR) on… read more here.
Keywords: basal ganglia; gastrointestinal bleeding; admission; ganglia hemorrhage ... See more keywords
Editorial for “Aberrant Hyperconnectivity of Amygdala‐Accumbens‐Pallidum Pathway Is Associated With Disorganized Nigrostriatal Pathway in Parkinson's Disease”
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27282
Abstract: As we enter the era of precision medicine, and in the absence of reliable disease-specific biomarkers, it is fundamental to identify probes helping characterize in vivo and noninvasively the anatomical–functional organization of the human brain… read more here.
Keywords: disease; amygdala accumbens; nigrostriatal pathway; pathway ... See more keywords
Basal ganglia involvement in the playfulness of juvenile rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24475
Abstract: Play is an important part of normal childhood development and can be readily studied in the laboratory rat in the form of rough‐and‐tumble play. Given the robust nature of rough‐and‐tumble play, it has often been… read more here.
Keywords: ganglia involvement; involvement playfulness; play; playfulness juvenile ... See more keywords
Altered basal ganglia infraslow oscillation and resting functional connectivity in complex regional pain syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25057
Abstract: Complex regional pain syndrome (CRPS) is a painful condition commonly accompanied by movement disturbances and often affects the upper limbs. The basal ganglia motor loop is central to movement, however, non‐motor basal ganglia loops are… read more here.
Keywords: connectivity; basal ganglia; motor; regional pain ... See more keywords
Oscillatory activity in the basal ganglia and deep brain stimulation
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.26714
Abstract: Over the past 10 years, research into the neurophysiology of the basal ganglia has provided new insights into the pathophysiology of movement disorders. The presence of pathological oscillations at specific frequencies has been linked to… read more here.
Keywords: basal; stimulation; activity basal; oscillatory activity ... See more keywords
Disruption in cerebellar and basal ganglia networks during a visuospatial task in cervical dystonia
Sign Up to like & getrecommendations! Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.26930
Abstract: Background: Although dystonia is traditionally conceptualized as a basal ganglia disorder, increasing interest has been directed at a different neural network node, the cerebellum, which may play a significant role in the pathophysiology of dystonia.… read more here.
Keywords: disruption cerebellar; dystonia; ganglia networks; cerebellar basal ... See more keywords