Targeted Metabolomics Reveals a Protective Role for Basal PPARα in Cholestasis Induced by α-Naphthylisothiocyanate.
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DOI: 10.1021/acs.jproteome.7b00838
Abstract: α-Naphthylisothiocyanate (ANIT) is an experimental agent used to induce intrahepatic cholestasis. The Ppara-null mouse line is widely employed to explore the physiological and pathological roles of PPARα. However, little is known about how PPARα influences… read more here.
Keywords: null mice; ppara null; mice; basal ppar ... See more keywords