Deep Brain Stimulation of the Nucleus Basalis of Meynert for Parkinson's Disease Dementia: A 36 Months Follow Up Study
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DOI: 10.1002/mdc3.13510
Abstract: Degeneration of the nucleus basalis of Meynert (NBM) and cortical cholinergic dysfunction are hallmarks of Parkinson's disease dementia (PDD). There is no effective therapy for PDD. Deep brain stimulation of the NBM (NBM‐DBS) has been… read more here.
Keywords: basalis meynert; disease dementia; parkinson disease; deep brain ... See more keywords
Cortical connectivity of the nucleus basalis of Meynert in Parkinson’s disease and Lewy body dementias
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DOI: 10.1093/brain/awaa411
Abstract: Abstract Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) are related conditions that are associated with cholinergic system dysfunction. Dysfunction of the nucleus basalis of Meynert (NBM), a basal forebrain structure that provides… read more here.
Keywords: connectivity; basalis meynert; nucleus basalis; disease ... See more keywords
Structural (dys)connectivity associates with cholinergic cell density in Alzheimer’s disease
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DOI: 10.1093/brain/awac093
Abstract: Abstract Cognitive deficits in Alzheimer’s disease, specifically amnestic (memory dominant) deficits, are associated with cholinergic degeneration in the basal forebrain. The cholinergic nucleus within the basal forebrain, the nucleus basalis of Meynert, exhibits local atrophy… read more here.
Keywords: basalis meynert; cholinergic cell; disease; alzheimer disease ... See more keywords
Reduction in Volume of Nucleus Basalis of Meynert Is Specific to Parkinson’s Disease and Progressive Supranuclear Palsy but Not to Multiple System Atrophy
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DOI: 10.3389/fnagi.2022.851788
Abstract: Objectives To study in vivo gray matter (GM) volumes of the nucleus basalis of Meynert (nbM) in different parkinsonian syndromes and assess their relationship with clinical variables. Methods T1-weighted magnetic resonance images from patients with… read more here.
Keywords: basalis meynert; progressive supranuclear; nbm volumes; parkinson disease ... See more keywords