Clinicopathological implications of TIM3+ tumor-infiltrating lymphocytes and the miR-455-5p/Galectin-9 axis in skull base chordoma patients
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-019-02349-1
Abstract: Chordoma is difficult to eradicate due to high local recurrence rates. The immune microenvironment is closely associated with tumor prognosis; however, its role in skull base chordoma is unknown. The expression of Galectin-9 (Gal9) and… read more here.
Keywords: mir 455; base chordoma; chordoma; skull base ... See more keywords
RARE-40. OUTCOMES AFTER PROTON THERAPY FOR SKULL-BASE CHORDOMA: A PROSPECTIVE STUDY
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.963
Abstract: We evaluated treatment outcomes following definitive or adjuvant high-dose, image-guided proton therapy in 91 patients with skull-base chordoma enrolled on a prospective outcomes tracking protocol and treated between February 2007 and February 2018. The median… read more here.
Keywords: therapy; proton therapy; skull base; base chordoma ... See more keywords
High systemic inflammation score is associated with adverse survival in skull base chordoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1046093
Abstract: Background The systemic inflammation score (SIS), based on preoperative lymphocyte to monocyte ratio (LMR) and albumin (ALB), was recently developed and is demonstrated to be a novel prognostic indicator in several cancers. However, data discussing… read more here.
Keywords: sis; base chordoma; chordoma; skull base ... See more keywords
PTEN is recognized as a prognostic-related biomarker and inhibits proliferation and invasiveness of skull base chordoma cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.1011845
Abstract: Objective This work aimed to examine the function of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) in skull base chordoma (SBC) at the clinical and cellular levels. Methods Totally 65 paraffin-embedded and 86… read more here.
Keywords: proliferation; chordoma; base chordoma; skull base ... See more keywords
Skull Base Chordoma: Long-Term Observation and Evaluation of Prognostic Factors after Surgical Resection
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DOI: 10.4103/0028-3886.333474
Abstract: Background: Skull base chordoma (SBC) is relatively rare and data on its clinical outcome after surgical resection and adjuvant radiotherapy are still limited. Objective: Analyzing the clinical postoperative outcome of SBC patients and defining prognostic… read more here.
Keywords: skull base; base chordoma; surgical resection; prognostic factors ... See more keywords