Contemporary surgical management of skull base chordomas—Anatomical reflections on a single center experience retrospective case series
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DOI: 10.1002/ca.23840
Abstract: Chordoma, a rare, locally aggressive tumor can affect the central skull base, usually centered at the midline. Complete surgical resection remains mainstay of therapy in case of primary as well as recurrent tumors. Owing to… read more here.
Keywords: skull base; case; anatomy; base chordomas ... See more keywords
C-Cbl and Cbl-b expression in skull base chordomas is associated with tumor progression and poor prognosis.
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DOI: 10.1016/j.humpath.2017.12.019
Abstract: Chordomas are rare, locally aggressive malignancies that are often difficult to eradicate. Surgery and radiotherapy are the first-line treatments, but the probability of local recurrence is high. According to our previous research, c-Cbl and Cbl-b… read more here.
Keywords: base chordomas; cbl; skull base; cbl cbl ... See more keywords
Surgical Strategy for Skull Base Chordomas : Transnasal Midline Approach or Transcranial Lateral Approach.
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DOI: 10.3340/jkns.2021.0187
Abstract: Objective The clinical management paradigm of skull base chordomas is still challenging. Surgical resection plays an important role of affecting the prognosis. Endonasal endoscopic approach (EEA) has gradually become the preferred surgical approach in most… read more here.
Keywords: skull base; transnasal midline; approach; base chordomas ... See more keywords
Clinical Grading System, Surgical Outcomes and Prognostic Analysis of Cranial Base Chordomas
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DOI: 10.3340/jkns.2021.0240
Abstract: Objective Cranial base chordomas are rare, but their treatment is challenging. Tumor recurrence is still common despite improvements in microsurgical techniques and postoperative radiotherapy. We retrospectively analyzed the course of treatment, overall survival, and recurrence/progression… read more here.
Keywords: survival; recurrence; grading system; base chordomas ... See more keywords
Methylation-based reclassification and risk stratification of skull-base chordomas
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DOI: 10.3389/fonc.2022.960005
Abstract: Background Skull-base chordomas are rare malignant bone cancers originating from the remnant of the notochord. Survival is variable, and clinical or molecular factors cannot reliably predict their outcomes. This study therefore identified epigenetic subtypes that… read more here.
Keywords: base chordomas; analysis; chordoma; skull base ... See more keywords