Structural exploration of arylsulfonamide-based ADAM17 inhibitors through validated comparative multi-QSAR modelling studies
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DOI: 10.1016/j.molstruc.2019.02.081
Abstract: Abstract Zinc-dependent ADAM17 takes part in a number of life-threatening conditions such as inflammatory diseases, cancer, Alzheimer's disease and rheumatoid arthritis. Therefore, ADAM17 may be a valuable target to design specific inhibitors for combating these… read more here.
Keywords: inhibitors validated; adam17 inhibitors; exploration arylsulfonamide; based adam17 ... See more keywords