Articles with "based adjuvant" as a keyword



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Comparative survival analysis of platinum‐based adjuvant chemotherapy for early‐stage squamous cell carcinoma and adenocarcinoma of the lung

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.4570

Abstract: Although cytotoxic platinum‐based adjuvant chemotherapy (pACT) has been recommended for patients with completely resected early‐stage (ES) non–small‐cell lung cancer (ES‐NSCLC), therapeutic regimens for NSCLC have evolved in the past two decades. The study was aimed… read more here.

Keywords: cell; based adjuvant; early stage; squamous cell ... See more keywords
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Predictive markers based on transcriptome modules for vinorelbine-based adjuvant chemotherapy for lung adenocarcinoma patients.

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Published in 2021 at "Lung cancer"

DOI: 10.1016/j.lungcan.2021.06.011

Abstract: OBJECTIVES Microtubule inhibitors (MTIs) are widely used as anti-cancer drugs for various types of tumors. Vinorelbine, an MTI, is utilized in postoperative adjuvant chemotherapy, especially for lung adenocarcinoma. However, no molecular markers are able to… read more here.

Keywords: lung adenocarcinoma; based adjuvant; adjuvant chemotherapy; lung ... See more keywords
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RNA-based adjuvant CV8102 enhances the immunogenicity of a licensed rabies vaccine in a first-in-human trial.

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Published in 2019 at "Vaccine"

DOI: 10.1016/j.vaccine.2019.02.024

Abstract: BACKGROUND We report the first-in-concept human trial of the safety, tolerability and immunogenicity when a novel TLR 7/8/RIG I agonist RNA-based adjuvant, CV8102, was administered alone or mixed with fractional doses of a licensed rabies… read more here.

Keywords: cv8102; based adjuvant; immunogenicity; rna based ... See more keywords

Platinum-based adjuvant therapy was efficient for triple-negative breast cancer: a meta-analysis from randomized controlled trials

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2115616

Abstract: ABSTRACT Triple-negative breast cancer (TNBC) is the most aggressive breast cancer. Neoadjuvant chemotherapy was widely accepted for treating TNBC. This systematic review and meta-analysis aimed to evaluate the efficacy, safety, and survival benefit of platinum-based… read more here.

Keywords: based adjuvant; adjuvant therapy; pbat; platinum based ... See more keywords
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Association between poorly differentiated clusters and efficacy of 5-fluorouracil-based adjuvant chemotherapy in stage III colorectal cancer

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Published in 2017 at "Japanese Journal of Clinical Oncology"

DOI: 10.1093/jjco/hyw209

Abstract: Abstract The efficacy of 5-fluorouracil-based adjuvant chemotherapy differs according to poorly differentiated cluster grade in colorectal cancer. Poorly differentiated cluster may have an important role in determining the most suitable treatment strategy. read more here.

Keywords: based adjuvant; poorly differentiated; adjuvant chemotherapy; colorectal cancer ... See more keywords

Rs11479 in Thymidine Phosphorylase Associated with Prognosis of Patients with Colorectal Cancer Who Received Capecitabine-Based Adjuvant Chemotherapy

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Published in 2023 at "Pharmacogenomics and Personalized Medicine"

DOI: 10.2147/pgpm.s397382

Abstract: Objective Thymidine Phosphorylase (TYMP) gene was of potential significance in the process of colorectal cancer (CRC) development and played an important role in capecitabine metabolism. This study was to identify the association between TYMP polymorphism… read more here.

Keywords: capecitabine; prognosis; based adjuvant; adjuvant chemotherapy ... See more keywords

The Immune Subtype Contributes to Distinct Overall Survival for Ovarian Cancer Patients With Platinum-Based Adjuvant Therapy

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.872991

Abstract: Objective Nowadays, platinum-based therapy has been widely used as the first-line therapy of ovarian cancer. However, the effect of the tumor microenvironment on platinum-based therapy remains unclear. In this study, we aim to investigate the… read more here.

Keywords: based adjuvant; ovarian cancer; therapy; adjuvant therapy ... See more keywords

5-Fluorouracil-based adjuvant chemotherapy improves the clinical outcomes of patients with lymphovascular invasion of upper urinary tract cancer and low expression of dihydropyrimidine dehydrogenase

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Published in 2019 at "Oncology Letters"

DOI: 10.3892/ol.2019.10086

Abstract: Lymphovascular invasion (LVI) by urothelial carcinoma of the upper urinary tract (UC-UUT) is associated with an unfavorable prognosis. However, a high proportion of patients with UC-UUT are unable to receive the recommended doses of cisplatin-based… read more here.

Keywords: expression; chemotherapy; fluorouracil; lymphovascular invasion ... See more keywords