An efficient PyAOP-based C4-amination method for direct access of oxidized 5MedC derivatives
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron"
DOI: 10.1016/j.tet.2018.10.046
Abstract: Abstract In the past decade, synthetic oxidized 5-MedC nucleosides and their derivatives have become essential tools for epigenetic research. The low efficacy of both conventional and newly reported BOP methods on C4-amination of these specific… read more here.
Keywords: 5medc derivatives; amination method; based amination; pyaop based ... See more keywords
Nondirected, Cu-Catalyzed sp3 C-H Aminations with Hydroxylamine-Based Amination Reagents: Catalytic and Mechanistic Studies.
Sign Up to like & getrecommendations! Published in 2017 at "Organometallics"
DOI: 10.1021/acs.organomet.7b00003
Abstract: This work demonstrates the use of hydroxylamine-based amination reagents RSO2NH-OAc for the nondirected, Cu-catalyzed amination of benzylic C-H bonds. The amination reagents can be prepared on a gram scale, are benchtop stable, and provide benzylic… read more here.
Keywords: amination reagents; hydroxylamine based; based amination; mechanistic studies ... See more keywords