Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-25548-9
Abstract: Restrictive anorexia nervosa is associated with reduced eating and severe body weight loss leading to a cachectic state. Hypothalamus plays a major role in the regulation of food intake and energy homeostasis. In the present… read more here.
Keywords: hypothalamus; mitochondrial dynamic; based anorexia; activity based ... See more keywords
Cortical reorganization of the glutamate synapse in the activity‐based anorexia rat model: Impact on cognition
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15605
Abstract: Patients suffering from anorexia nervosa (AN) display altered neural activity, morphological, and functional connectivity in the fronto‐striatal circuit. In addition, hypoglutamatergic transmission and aberrant excitability of the medial prefrontal cortex (mPFC) observed in AN patients… read more here.
Keywords: glutamate; based anorexia; activity based; activity ... See more keywords
The BDNF Val66Met Polymorphism Does Not Increase Susceptibility to Activity-Based Anorexia in Rats
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11050623
Abstract: Simple Summary Genetic animal models are a valuable tool for understanding how human pathologies develop. The type of animal model chosen is important for uncovering effects specific to certain behaviours and neurobiological functions. A polymorphism… read more here.
Keywords: polymorphism; based anorexia; bdnf val66met; activity based ... See more keywords
Glutamine, but not Branched-Chain Amino Acids, Restores Intestinal Barrier Function during Activity-Based Anorexia
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DOI: 10.3390/nu11061348
Abstract: Background: During activity-based anorexia (ABA) in mice, enhanced paracellular permeability and reduced protein synthesis have been shown in the colon while the gut–brain axis has received increasing attention in the regulation of intestinal and mood… read more here.
Keywords: amino acids; based anorexia; activity based; chain amino ... See more keywords