Recent advances of platinum-based anticancer complexes in combinational multimodal therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300253
Abstract: Platinum drugs with manifest therapeutic effects are widely used, but their systemic toxicity and the drug resistance acquired by cancer cells limit their clinical applications. Thus, the exploration on appropriate methods and strategies to overcome… read more here.
Keywords: anticancer complexes; based anticancer; therapy; platinum drugs ... See more keywords
Photoactivated platinum-based anticancer drugs
Sign Up to like & getrecommendations! Published in 2018 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2018.08.009
Abstract: Abstract Following the serendipitous discovery of the anticancer drug, cisplatin, numerous platinum(II) complexes have been synthesized and some of them, such as carboplatin, oxaliplatin, nedaplatin, heptaplatin and lobaplatin, have been clinically approved either locally or… read more here.
Keywords: platinum; platinum based; based anticancer; anticancer drugs ... See more keywords
Recent advances in the chemistry of iron-based chemotherapeutic agents
Sign Up to like & getrecommendations! Published in 2020 at "Coordination Chemistry Reviews"
DOI: 10.1016/j.ccr.2020.213339
Abstract: Abstract The discovery of cisplatin followed by its success in anticancer therapy laid the foundation of metal-based drug design and development. Further research led to discovery of other platinum containing complexes, namely, carboplatin and oxaliplatin.… read more here.
Keywords: chemotherapeutic agents; based anticancer; chemistry; iron ... See more keywords
Recent advances in chalcone-based anticancer heterocycles: A structural and molecular target perspective.
Sign Up to like & getrecommendations! Published in 2021 at "Current medicinal chemistry"
DOI: 10.2174/0929867328666210322102836
Abstract: Chalcones are an interesting class of compounds endowed with a plethora of biological activities beneficial to human health. These chemo types have continued to attract increased research attention over the years; hence, numerous natural and… read more here.
Keywords: based anticancer; recent advances; advances chalcone; anticancer ... See more keywords
Novel Phthalic-Based Anticancer Tyrosine Kinase Inhibitors: Design, Synthesis and Biological Activity
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DOI: 10.3390/cimb45030117
Abstract: In this work, fragments of isophthalic and terephthalic acids are proposed as a structural scaffold to develop potential inhibitors of protein kinases. Novel isophthalic and terephthalic acid derivatives were designed as type-2 protein kinase inhibitors,… read more here.
Keywords: based anticancer; kinase inhibitors; phthalic based; kinase ... See more keywords
Target-Based Anticancer Indole Derivatives for the Development of Anti-Glioblastoma Agents
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DOI: 10.3390/molecules28062587
Abstract: Glioblastoma (GBM) is the most aggressive and frequent primary brain tumor, with a poor prognosis and the highest mortality rate. Currently, GBM therapy consists of surgical resection of the tumor, radiotherapy, and adjuvant chemotherapy with… read more here.
Keywords: based anticancer; development; target based; anti gbm ... See more keywords
Light-Triggered Polymersome-Based Anticancer Therapeutics Delivery
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12050836
Abstract: Polymersomes are biomimetic cell membrane-like model structures that are self-assembled stepwise from amphiphilic copolymers. These polymeric (nano)carriers have gained the scientific community’s attention due to their biocompatibility, versatility, and higher stability than liposomes. Their tunable… read more here.
Keywords: based anticancer; triggered polymersome; light; polymersome based ... See more keywords