A comparison of popular TDT‐generalizations for family‐based association analysis
Sign Up to like & getrecommendations! Published in 2019 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22181
Abstract: The transmission disequilibrium test (TDT) is the gold standard for testing the association between a genetic variant and disease in samples consisting of affected individuals and their parents. In practice, more complex pedigree structures, that… read more here.
Keywords: based association; tdt generalizations; association; generalizations family ... See more keywords
Family‐based Association between Allele T of rs4646536 in CYP27B1 and vitamin D deficiency
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22898
Abstract: The circulating concentration of 25(OH)D is widely applied to indicate the vitamin D status, as the directly metabolic genes of 25(OH)D, CYP2R1, and CYP27B1 are associated with the concentration of 25(OH)D. However, the contributions of… read more here.
Keywords: cyp27b1 vitamin; based association; cyp27b1; family based ... See more keywords
An adaptive microbiome α-diversity-based association analysis method
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36355-7
Abstract: To relate microbial diversity with various host traits of interest (e.g., phenotypes, clinical interventions, environmental factors) is a critical step for generic assessments about the disparity in human microbiota among different populations. The performance of… read more here.
Keywords: diversity; microbiome diversity; based association; association ... See more keywords
OPATs: Omnibus P-value association tests
Sign Up to like & getrecommendations! Published in 2019 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbx068
Abstract: Abstract Combining statistical significances (P‐values) from a set of single‐locus association tests in genome‐wide association studies is a proof‐of‐principle method for identifying disease‐associated genomic segments, functional genes and biological pathways. We review P‐value combinations for… read more here.
Keywords: based association; association; association tests; value combinations ... See more keywords
ExPheWas: a platform for cis-Mendelian randomization and gene-based association scans
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac289
Abstract: Abstract Establishing the relationship between protein-coding genes and phenotypes has the potential to inform on the molecular etiology of diseases. Here, we describe ExPheWas (exphewas.ca), a gene-based phenome-wide association study browser and platform that enables… read more here.
Keywords: based association; mendelian randomization; gene; gene based ... See more keywords
LDAK-GBAT: fast and powerful gene-based association testing using summary statistics
Sign Up to like & getrecommendations! Published in 2022 at "American journal of human genetics"
DOI: 10.1101/2022.07.01.22277161
Abstract: We present LDAK-GBAT, a novel tool for gene-based association testing using summary statistics from genome-wide association studies. We first evaluate LDAK-GBAT using ten phenotypes from the UK Biobank. We show that LDAK-GBAT is computationally efficient,… read more here.
Keywords: based association; association testing; gbat; gene based ... See more keywords
In silico genome-wide gene-based association analysis reveals new genes predisposing to CAD.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical genetics"
DOI: 10.1111/cge.14073
Abstract: Genome-wide association analyses (GWAS) have identified more than 300 single nucleotide polymorphisms at 163 independent loci associated with coronary artery disease (CAD). However, there is no full understanding about the causal genes for CAD and… read more here.
Keywords: analysis; based association; cad; gene based ... See more keywords
Enterprise Operating State Evaluation Based on Association Rule Algorithm and Data Set
Sign Up to like & getrecommendations! Published in 2022 at "Computational Intelligence and Neuroscience"
DOI: 10.1155/2022/1300068
Abstract: In order to further improve the evaluation quality of enterprise operating efficiency, reduce the error items and invalid items of partition, and improve the objectivity of operating condition evaluation, this study takes listed enterprises as… read more here.
Keywords: based association; rule algorithm; evaluation; association rule ... See more keywords
Information Reconstruction of Student Management Work Based on Association Rules Mining
Sign Up to like & getrecommendations! Published in 2022 at "Computational Intelligence and Neuroscience"
DOI: 10.1155/2022/2318515
Abstract: In recent years, as the country has paid more and more attention to the education, informatization of student management has become more and more important. This article aims to study how to reconstruct the informatization… read more here.
Keywords: based association; management; information; student management ... See more keywords
DNA-based association and description of the larval stage of Apatania theischingerorum Malicky 1981 (Trichoptera, Apataniidae), with notes on its ecology.
Sign Up to like & getrecommendations! Published in 2018 at "Zootaxa"
DOI: 10.11646/zootaxa.4418.2.5
Abstract: The hitherto unknown larva of Apatania theischingerorum Malicky 1981 is described, based on the association with adult females using sequence data from the mitochondrial cytochrome c oxidase region. Genetic data confirmed the distinct status of… read more here.
Keywords: based association; malicky 1981; theischingerorum malicky; apatania theischingerorum ... See more keywords
Cluster of Differentiation 24 Polymorphism Has No Significant Association with Chronic Hepatitis B Virus Infection in the Chinese Han Population: A Family-Based Association Study
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s368392
Abstract: Objective Studies have shown that cluster of differentiation (CD) 24 gene polymorphism is associated with several diseases. Among these, chronic hepatitis B (CHB) infection has not been investigated. This study aimed to assess the function… read more here.
Keywords: based association; polymorphism; chb; family based ... See more keywords