Effect of RNAi-based β-catenin inhibition on immunosuppressive Wnt-activated tumors in combination with IDOi/PD-1 immunotherapy.
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DOI: 10.1200/jco.2018.36.15_suppl.e15038
Abstract: e15038Background: Wnt/β-catenin pathway activation has been correlated with T-cell exclusion across most human tumors. Additionally, Wnt signaling promotes constitutive IDO1 expression in some tumo... read more here.
Keywords: effect rnai; catenin inhibition; immunosuppressive wnt; based catenin ... See more keywords