In Vitro-In Vivo Correlation in Cocrystal Dissolution: Consideration of Drug Release Profiles Based on Coformer Dissolution and Absorption Behavior.
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DOI: 10.1021/acs.molpharmaceut.1c00537
Abstract: This study assessed the in vitro-in vivo correlation in cocrystal dissolution based on the coformer behavior. 4-Aminobenzoic acid (4ABA) was used as a coformer. Cocrystals of poorly water-soluble drugs with 4ABA, ketoconazole cocrystal (KTZ-4ABA), posaconazole… read more here.
Keywords: cocrystal dissolution; vitro vivo; based coformer; ktz 4aba ... See more keywords